Amplify Your Upstream Ecosystem
Our Millipore Mobius® 3L Single-Use Bioreactors are
the next step in developing your molecule
Know Your Cell Culture Media
When developing your monoclonal antibody, amplifying your upstream process development will help save time, optimize performance, improve sustainability, and lay a strong foundation for downstream processes.
Our upstream ecosystem - comprised of cell line and media platforms, cell line development, product characterization services, bioreactors, single-use mixers, process development expertise, and next generation processing programs will help you get your upstream process right the first time.
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Now that you've CHOZN your cell line, did you know we can support your journey with benchtop bioreactors? Our Millipore Mobius® 3L Single-Use Bioreactors are the next step in developing your molecule. Request a sample of our Millipore Mobius® 3L Single-Use Bioreactors to try out today.
The Mobius® Single-Use 3 L bioreactor family is a benchtop (3 L), that enables cell culturing capabilities for early process development. Our bioreactor platform has been designed to ensure that ease-of-use and operational flexibility at small scale can be translated to full scale production. Our bioreactor enables the cells to be cultured under tightly controlled conditions, improving cell yields and reducing batch variability.
Cellvento® ModiFeed Prime COMP is a chemically defined feed formulation containing only components of nonanimal origin. It does not contain hydrolysates, phenol red, 2-mercaptoethanol, or glucose ensuring batch-to-batch consistency. The product is intended for use in the development and manufacturing of monoclonal antibodies and next-generation biopharmaceuticals in Chinese Hamster Ovary (CHO) cell-based expression systems.
The CHOZN® Expression platform is a mammalian cell expression system based on CHO cells (Chinese Hamster Ovary) for fast and easy selection and scale up of stable clones producing high levels of recombinant proteins. This platform is
- Highly productive
- Highly robust and stable
- Proven scalability
- cGMP cell banked
- Paired with optimized media & feeds
To accelerate your biopharmaceutical development we offer an Integrated Upstream Solution - CHOZN® & UCOE® Combined Platform
- Accelerate your cell line development by increased efficiency of isolating high producing clones. Eightfold more clone candidate pools and twice the number of clones expressing more than 3 g/L were obtained with the combined platform.
- Increase cell line development success with hard-to produce molecules
- Achieve high and stable titers to expedite your cGMP manufacturing with fewer resources
Cell culture media are important for process efficiency and mAb quality. Production media support initial cell growth and production, while the feed replenish depleted nutrients required for cellular function and maintain and extend the production phase in fed-batch mode.
EX-CELL® Advanced and Cellvento® 4CHO platform media and feeds support growth and productivity across a diverse set of CHO cells in fed-batch cultures. The high concentrated feed allows a reduction of the added feed volume thereby increasing the volumetric productivity.
- Chemically defined
- Consistent cell growth and performance
- Available in powder or compacted format
- Robust scalability
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