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  • Mycobacterium kansasii infection of the spine in a patient with sarcoidosis: a case report and literature review.

Mycobacterium kansasii infection of the spine in a patient with sarcoidosis: a case report and literature review.

Journal of surgical orthopaedic advances (2014-08-26)
Wajeeh R Bakhsh, Addisu Mesfin
摘要

Mycobacterium kansasii is an acid-fast bacillus most commonly associated with pulmonary pathology. Infection of the spine is exceedingly rare, with just three reported cases, two of which were in human immunodeficiency virus and acquired immunodeficiency syndrome patients. This case report presents a case of vertebral osteomyelitis secondary to M. kansasii infection and reviews existing literature on this pathogen. The patient, a 37-year-old male with sarcoidosis, sustained a M. kansasii infection of the spine, resulting in vertebral osteomyelitis of L1 and L2 and discitis of the L1-L2 disc. This finding was confirmed by bone and intervertebral disc biopsy. Initially, the patient was thought to have a compression fracture of L2. However, the decision to perform a biopsy was made because of the patient's persistent febrile episodes and magnetic resonance imaging findings. The patient did not have any neurological deficits. He was successfully treated with antimicrobials, with no recurrent symptoms at 2-year follow-up. This case is the first reported case of a M. kansasii infection of the spine in a patient with sarcoidosis.

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Sigma-Aldrich
乙胺丁醇 二盐酸盐, antimycobacterial
Supelco
异烟肼, analytical standard, ≥99% (TLC)
异烟肼, European Pharmacopoeia (EP) Reference Standard
乙胺丁醇 盐酸盐, European Pharmacopoeia (EP) Reference Standard
乙胺丁醇, European Pharmacopoeia (EP) Reference Standard
Supelco
异烟肼, Vetec, reagent grade, 98%