所有图片(1)
别名:
乙胺丁醇 二盐酸盐, 2,2＃8242;-(1,2- Ethanediyldiimino）双-1-丁醇 二盐酸盐, Emb
经验公式（希尔记法）:
C10H24N2O2 · 2HCl
推荐产品
等级
pharmaceutical primary standard
API类
ethambutol
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-8°C
SMILES字符串
CC[C@@H](CO)NCCN[C@H](CO)CC.Cl.Cl
InChI
1S/C10H24N2O2.2ClH/c1-3-9(7-13)11-5-6-12-10(4-2)8-14;;/h9-14H,3-8H2,1-2H3;2*1H/t9-,10-;;/m0../s1
InChI key
AUAHHJJRFHRVPV-BZDVOYDHSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
乙胺丁醇是一种分枝杆菌抗菌剂，与其他抗生素联合使用可治疗结核病，减缓耐药性的发展进程。在中国结核病发病率最高的地区，长期用于研究耐多药结核病（MDR-TB）。
生化/生理作用
乙胺丁醇对活跃生长的结核杆菌具有抗菌作用。分枝菌酸附着在阿拉伯半乳聚糖的 D-阿拉伯糖残基的 5′-羟基上，并在细胞壁中形成分枝酸- 阿拉伯半乳糖-肽聚糖复合层。乙胺丁醇通过抑制阿拉伯糖基转移酶，特别是分枝杆菌中的阿拉伯糖基转移酶，干扰阿拉伯半乳聚糖的合成，通过干扰分枝杆菌细胞壁中的阿拉伯半乳聚糖的生物合成，并导致细胞壁渗透性增加。
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
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说明
价格
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Wajeeh R Bakhsh et al.
Journal of surgical orthopaedic advances, 23(3), 162-165 (2014-08-26)
Mycobacterium kansasii is an acid-fast bacillus most commonly associated with pulmonary pathology. Infection of the spine is exceedingly rare, with just three reported cases, two of which were in human immunodeficiency virus and acquired immunodeficiency syndrome patients. This case report
Joshua R Francis et al.
The Medical journal of Australia, 200(6), 328-332 (2014-04-08)
OBJECTIVE To describe the epidemiology, clinical features, health care resource use, treatment and outcomes of multidrug-resistant tuberculosis (MDR-TB) cases diagnosed in Western Australia, compared with matched controls with drug-susceptible TB. Retrospective case-control study of all MDR-TB cases notified in WA
N Guo et al.
Letters in applied microbiology, 58(4), 344-349 (2013-12-18)
Previous studies have shown that isoimperatorin (IO), a furanocoumarin isolated from several medicinal plants, has antimycobacterial activity against Mycobacterium tuberculosis strain H37Rv (ATCC 27294). This study demonstrated that IO has antimycobacterial activity against 2 drug-sensitive and 6 drug-resistant isolates, with
Partha Pal et al.
The American journal of tropical medicine and hygiene, 90(5), 788-789 (2014-05-09)
A 60-year-old woman presented with a painful lump of 4 months duration in her right breast. She denied any history of breast trauma or family history of breast cancer. Physical examination detected a firm, tender mass in the upper inner
Corinne S Merle et al.
The New England journal of medicine, 371(17), 1588-1598 (2014-10-23)
Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin-sensitive pulmonary tuberculosis. We conducted a
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