- A facile copper-catalyzed one-pot domino synthesis of 5,12-dihydroindolo[2,1-b]quinazolines.
A facile copper-catalyzed one-pot domino synthesis of 5,12-dihydroindolo[2,1-b]quinazolines.
Organic letters (2012-03-08)
Min Jiang, Jian Li, Feng Wang, Yichao Zhao, Feng Zhao, Xiaochun Dong, Weili Zhao
PMID22394154
摘要
A domino synthesis of 5,12-dihydroindolo[2,1-b]quinazoline derivatives via copper-catalyzed Ullmann-type intermolecular C-C and intramolecular C-N couplings is reported. Good yields of various 5,12-dihydroindolo[2,1-b]quinazoline derivatives were obtained. Reaction scopes, limitations, and the reaction mechanism are discussed.