Fate of desmosomal proteins in apoptotic epidermal cells.

Fate of desmosomal proteins in apoptotic epidermal cells.

Methods in molecular biology (Clifton, N.J.) (2004-10-27)

Jörg Weiske, Otmar Huber

摘要

In epidermal cells desmosomes represent major sites of basolateral cell-cell contacts that play an important role for epidermal homeostasis. Excess or damaged cells are often removed by apoptosis. To release apoptotic cells from the tissue, intercellular contacts have to be broken. Here detailed protocols to analyze desmosomal proteins in apoptotic cells are described.

材料

货号

品牌

产品描述

C9911

Sigma-Aldrich

(S)-(+)-喜树碱, ≥90% (HPLC), powder

264155

Sigma-Aldrich

半胱氨酸蛋白酶-3抑制物II, The Caspase-3 Inhibitor II, also referenced under CAS 210344-95-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.

444250

Sigma-Aldrich

MMP Inhibitor I, The MMP Inhibitor I controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.