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Merck
CN

1205003

USP

(+)-顺式-地尔硫卓 盐酸盐

United States Pharmacopeia (USP) Reference Standard

别名:

(2S,3S)-(+)-顺式-3-乙酰氧基-5-(2-二甲基氨基乙基)-2,3-二氢-2-(4-甲氧基苯基)-1,5-苯并硫氮杂-4(5H)- 酮 盐酸盐, CRD-401

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关于此项目

经验公式(希尔记法):
C22H26N2O4S · HCl
化学文摘社编号:
分子量:
450.98
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4228706
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InChI key

HDRXZJPWHTXQRI-BHDTVMLSSA-N

InChI

1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1

SMILES string

Cl.COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O

grade

pharmaceutical primary standard

API family

diltiazem

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Diltiazem hydrochloride.
B F McGraw
Drug intelligence & clinical pharmacy, 16(5), 366-370 (1982-05-01)
Jaime A Foushee et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 72(6), 483-486 (2015-03-05)
The physical compatibility of cisatracurium with selected drugs during simulated Y-site administration was studied. Study drugs were selected based on the lack of physical compatibility data with cisatracurium and their use in intensive care units. Test admixtures were prepared by
Clinical evaluation of losartan and diltiazem on the development of T-wave memory by right apical ventricular pacing.
Pablo A Chiale et al.
Journal of the American College of Cardiology, 63(18), 1929-1931 (2014-03-13)
B J McAuley et al.
Pharmacotherapy, 2(3), 121-133 (1982-05-01)
Diltiazem, a calcium channel blocking agent, has potent cardiovascular effects that are directly related to its influence on vascular smooth muscle, ventricular myocardium, and specialized conducting tissue. It causes coronary and peripheral vasodilation, has a negative chronotropic and dromotropic effect
K Adibkia et al.
Drug research, 64(4), 203-207 (2013-09-13)
The aim of this study was to design and evaluate diltiazem hydrochloride controlled porosity osmotic pump (CPOP) system employing a new coating technique named the micro suspension coating method. In this method the fast dissolving pore formers were suspended in

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