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经验公式(希尔记法):
C22H26N2O4S · HCl
化学文摘社编号:
分子量:
450.98
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4228706
产品名称
(+)-顺式-地尔硫卓 盐酸盐, United States Pharmacopeia (USP) Reference Standard
InChI key
HDRXZJPWHTXQRI-BHDTVMLSSA-N
InChI
1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1
SMILES string
Cl.COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O
grade
pharmaceutical primary standard
API family
diltiazem
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Diltiazem hydrochloride.
B F McGraw
Drug intelligence & clinical pharmacy, 16(5), 366-370 (1982-05-01)
[Diltiazem hydrochloride: synthetic and pharmacological studies and development].
K Abe et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 108(8), 716-732 (1988-08-01)
K Adibkia et al.
Drug research, 64(4), 203-207 (2013-09-13)
The aim of this study was to design and evaluate diltiazem hydrochloride controlled porosity osmotic pump (CPOP) system employing a new coating technique named the micro suspension coating method. In this method the fast dissolving pore formers were suspended in
Takeshi Ogura et al.
Acta neurochirurgica. Supplement, 120, 47-50 (2014-11-05)
This study evaluated the effect of diltiazem, a calcium antagonist, on sympathetic activity in patients with aneurysmal subarachnoid hemorrhage (SAH) during the hyperacute stage. Of patients with aneurysmal SAH who underwent aneurysm repair between August 2008 and June 2011, 119
Hossein Gandomkar et al.
Diseases of the colon and rectum, 58(2), 228-234 (2015-01-15)
The aim of this study is to evaluate the effectiveness and complications associated with combined topical diltiazem cream and botulinum toxin A injection versus partial lateral internal sphincterotomy in chronic anal fissure. This study is a parallel, randomized controlled trial
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