CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
别名:
CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, LQT8, TS
物种:
Human CACNA1C (775), Mouse Cacna1c (12288), Rat Cacna1c (24239), Zebrafish cacna1c (170581), domestic guinea pig Cacna1c (100135490), dog CACNA1C (403516), naked mole-rat Cacna1c (101717129), chicken CACNA1C (395891), Horse CACNA1C (100049924), domestic cat CACNA1C (101082923) ...展开
UniProtKB ID:
基因ID:
- Human(775) Summary: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
- Mouse(12288) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Rat(24239) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Zebrafish(170581) calcium channel, voltage-dependent, L type, alpha 1C subunit
- domestic guinea pig(100135490) calcium channel, voltage-dependent, L type, alpha 1C subunit
- dog(403516) calcium channel, voltage-dependent, L type, alpha 1C subunit
- naked mole-rat(101717129) calcium channel, voltage-dependent, L type, alpha 1C subunit
- chicken(395891) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Horse(100049924) calcium channel, voltage-dependent, L type, alpha 1C subunit
- domestic cat(101082923) calcium channel, voltage-dependent, L type, alpha 1C subunit
- cow(408015) calcium channel, voltage-dependent, L type, alpha 1C subunit
- sheep(101116562) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Goat(100861292) calcium channel, voltage-dependent, L type, alpha 1C subunit
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Small Molecule - Allosteric Modulator
货号
说明
物种
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
加巴喷丁标准液 CRM 溶液, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Small Molecule - Antagonist
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
抗 钙通道（α 1C 亚基）（L-型电压门控 Ca2+ 通道） 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Anti-CACNA1C antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-Calcium Channel (Cardiac α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
rabbit, rat
应用
immunoprecipitation (IP)
western blot
western blot
Anti-Cav1.2 alpha1c, clone 8F9.1 Antibody, clone 8F9.1, from mouse,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-Calcium Channel Antibody, Voltage Gated α 1C, Chemicon®, from rabbit,
物种反应性
human, mouse, rabbit, rat
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Blocker
货号
说明
物种
Verapamil hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human