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1287303

USP

Gabapentin

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
1-(Aminomethyl)-cyclohexaneacetic acid, Neurontin
Empirical Formula (Hill Notation):
C9H17NO2
CAS Number:
60142-96-3
Molecular Weight:
171.24
Beilstein:
2359739
MDL number:
MFCD00865286
UNSPSC Code:
41116107
PubChem Substance ID:
329749919
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

gabapentin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

NCC1(CC(O)=O)CCCCC1

InChI

1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)

InChI key

UGJMXCAKCUNAIE-UHFFFAOYSA-N

Gene Information

human ... CACNA1A(773) , CACNA1B(774) , CACNA1C(775) , CACNA1D(776) , CACNA1E(777) , CACNA1F(778) , CACNA1G(8913) , CACNA1H(8912) , CACNA1I(8911) , CACNA1S(779) , CACNA2D1(781) , CACNA2D2(9254) , CACNA2D3(55799) , CACNA2D4(93589) , CACNB1(782) , CACNB2(783) , CACNB3(784) , CACNB4(785) , CACNG1(786) , CACNG2(10369) , CACNG3(10368) , CACNG4(27092) , CACNG5(27091) , CACNG6(59285) , CACNG7(59284) , CACNG8(59283)

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Related Categories

Application

Gabapentin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Gabapentin Capsules
  • Gabapentin Tablets
  • Gabapentin Compounded Cream
  • Gabapentin Compounded Oral Suspension

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Description
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1287325

Gabapentin Related Compound A, United States Pharmacopeia (USP) Reference Standard

1287347

Gabapentin Related Compound B, United States Pharmacopeia (USP) Reference Standard

1287358

Gabapentin Related Compound D, United States Pharmacopeia (USP) Reference Standard

1287369

Gabapentin Related Compound E, United States Pharmacopeia (USP) Reference Standard

Y0001281

Gabapentin impurity A, European Pharmacopoeia (EP) Reference Standard

Y0001348

Gabapentin impurity B, European Pharmacopoeia (EP) Reference Standard

PHR1322

Gabapentin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001280

Gabapentin, European Pharmacopoeia (EP) Reference Standard

Y0001349

Gabapentin impurity D, European Pharmacopoeia (EP) Reference Standard

1154649

Cyclohexanecarboxylic acid, United States Pharmacopeia (USP) Reference Standard

PHR2013

Gabapentin Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2011

Gabapentin Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2012

Gabapentin Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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ESTIMATION OF GABAPENTIN IN HUMAN PLASMA USING LC-MS/MS METHOD.
Das, Binaya.
Asian Journal of Pharmaceutical and Clinical Research, 6.3, 213-216 (2013)
N S Gee et al.
The Journal of biological chemistry, 271(10), 5768-5776 (1996-03-08)
Gabapentin (1-(aminomethyl)cyclohexane acetic acid; Neurontin) is a novel anticonvulsant drug, with a mechanism of action apparently dissimilar to that of other antiepileptic agents. We report here the isolation and characterization of a [3H]gabapentin-binding protein from pig cerebral cortex membranes. The
Dennis F Thompson et al.
The Annals of pharmacotherapy, 47(6), 897-903 (2013-05-16)
To determine whether gabapentin is effective in the treatment of persistent or intractable hiccups. A search of MEDLINE (1966-March 2013) using the MeSH search terms gabapentin, hiccups, and hiccups/drug therapy was performed. Additional databases searched included Web of Science (1945-March
Sheeba Anand
The American journal of hospice & palliative care, 30(2), 192-196 (2012-05-05)
Itch/pruritus can be very distressing in palliative care population and often is difficult to treat. Conventional antihistamines lack efficacy. Cutaneous and central pathogenesis of itch is extremely complex and unclear, making its treatment challenging. Neuronal mechanisms have been identified in
Hance Clarke et al.
Anesthesia and analgesia, 115(2), 428-442 (2012-03-15)
Many clinical trials have demonstrated the effectiveness of gabapentin and pregabalin administration in the perioperative period as an adjunct to reduce acute postoperative pain. However, very few clinical trials have examined the use of gabapentin and pregabalin for the prevention
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