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Merck
CN

BP1210

利托那韦

British Pharmacopoeia (BP) Reference Standard

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别名:
1,3-噻唑-5-基甲基 N-[(2S,3S,5S)-3-羟基-5-[[(2S)-3-甲基-2-[[甲基-[(2-丙-2-基-1,3-噻唑-4-基)甲基]氨基甲酰基]氨基]丁酰基]氨基]-1,6-二苯基己基-2-基]氨基甲酸酯
经验公式(希尔记法):
C37H48N6O5S2
分子量:
720.94
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

质量水平

Agency

BP

API类

ritonavir

形式

solid

保质期

limited shelf life, expiry date on the label

包装

pkg of 100 mg

制造商/商品名称

BP

储存条件

dry at room temperature

颜色

off-white

mp

122-126  °C

溶解性

ethanol: soluble
isopropanol: soluble
methanol: soluble

密度

1.239 g/cm3 at 20 °C

应用

pharmaceutical
pharmaceutical small molecule

格式

neat

运输

ambient

储存温度

2-8°C

InChI

1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1

InChI key

NCDNCNXCDXHOMX-XGKFQTDJSA-N

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一般描述

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Ritonavir BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Ritonavir Oral Solution
  • Ritonavir Tablets
  • 包装

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他说明

    Sales restrictions may apply.

    象形图

    Exclamation mark

    警示用语:

    Warning

    危险声明

    危险分类

    Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

    WGK

    WGK 3

    闪点(°F)

    Not applicable

    闪点(°C)

    Not applicable


    分析证书(COA)

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    访问文档库

    RP-HPLC method development and validation for simultaneous estimation of Lopinavir and Ritonavir in tablet dosage form
    Bindu MJ, et al.
    International Journal of Science and Engineering Applications, 5(1), 77-77 (2017)
    HPTLC method for simultaneous determination of lopinavir and ritonavir in capsule dosage form
    Sulebhavikar VA, et al.
    Journal of Chemistry, 5(4), 706-712 (2008)

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