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主要文件

BP1210

利托那韦

British Pharmacopoeia (BP) Reference Standard

别名:

1,3-噻唑-5-基甲基 N-[（2S,3S,5S）-3-羟基-5-[[（2S）-3-甲基-2-[[甲基-[（2-丙-2-基-1,3-噻唑-4-基）甲基]氨基甲酰基]氨基]丁酰基]氨基]-1,6-二苯基己基-2-基]氨基甲酸酯

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About This Item

经验公式（希尔记法）:
C37H48N6O5S2
CAS号:
155213-67-5
分子量:
720.94
MDL编号:
MFCD08694944
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

质量水平

100

Agency

BP

API类

ritonavir

表单

solid

保质期

limited shelf life, expiry date on the label

包装

pkg of 100 mg

制造商/商品名称

BP

储存条件

dry at room temperature

颜色

off-white

mp

122-126  °C

溶解性

ethanol: soluble
isopropanol: soluble
methanol: soluble

密度

1.239 g/cm3 at 20 °C

应用

pharmaceutical
pharmaceutical small molecule

包装形式

neat

运输

ambient

储存温度

2-8°C

SMILES字符串

[s]1c(nc(c1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@@H](NC(=O)OCc4[s]cnc4)Cc3ccccc3)Cc2ccccc2)C(C)C

InChI

1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1

InChI key

NCDNCNXCDXHOMX-XGKFQTDJSA-N

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相关类别

一般描述

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Ritonavir BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Ritonavir Oral Solution
  • Ritonavir Tablets

    • 包装

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他说明

    Sales restrictions may apply.

    象形图

    Exclamation mark
    GHS07

    警示用语：

    Warning

    危险声明

    H302 + H312 + H332

    危险分类

    Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

    储存分类代码

    11 - Combustible Solids

    WGK

    WGK 3

    闪点(°F)

    Not applicable

    闪点(°C)

    Not applicable

    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    访问文档库

    RP-HPLC method development and validation for simultaneous estimation of Lopinavir and Ritonavir in tablet dosage form
    Bindu MJ, et al.
    International Journal of Science and Engineering Applications, 5(1), 77-77 (2017)
    HPTLC method for simultaneous determination of lopinavir and ritonavir in capsule dosage form
    Sulebhavikar VA, et al.
    Journal of Chemistry, 5(4), 706-712 (2008)

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