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Merck
CN
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主要文件

1604803

USP

利托那韦

United States Pharmacopeia (USP) Reference Standard

别名:

1,3-噻唑-5-基甲基 N-[（2S,3S,5S）-3-羟基-5-[[（2S）-3-甲基-2-[[甲基-[（2-丙-2-基-1,3-噻唑-4-基）甲基]氨基甲酰基]氨基]丁酰基]氨基]-1,6-二苯基己基-2-基]氨基甲酸酯

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About This Item

经验公式（希尔记法）:
C37H48N6O5S2
CAS号:
155213-67-5
分子量:
720.94
MDL编号:
MFCD08694944
UNSPSC代码:
41116107
NACRES:
NA.24

生物来源

synthetic

等级

pharmaceutical primary standard

Agency

USP

蒸汽压

<0.0000001 kPa ( 25 °C)

API类

ritonavir

表单

powder

包装

pkg of 200 mg

制造商/商品名称

USP

储存条件

protect from light

颜色

white to tan

溶解性

acetonitrile: slightly soluble
ethanol: freely soluble
methanol: freely soluble
methylene chloride: freely soluble
water: practically insoluble

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

[s]1c(nc(c1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@@H](NC(=O)OCc4[s]cnc4)Cc3ccccc3)Cc2ccccc2)C(C)C

InChI

1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1

InChI key

NCDNCNXCDXHOMX-XGKFQTDJSA-N

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.

应用

Ritonavir USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Ritonavir Capsules
  • Ritonavir Tablets
  • Ritonavir Oral Solution
  • Lopinavir and Ritonavir Tablets
  • Lopinavir and Ritonavir Oral Solution

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302 + H312 + H332

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

Lot/Batch Number

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访问文档库

Lopinavir and Ritonavir Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(4), 2670-2670 (2013)
Ritonavir
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 3912-3912 (2020)
Ritonavir USP Monograph
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 3880-3880 (2020)
Lopinavir and Ritonavir Oral Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(4), 2666-2666 (2015)
Ritonavir Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(4), 3920-3920 (2013)
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