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Merck
CN

51603-U

Supelco

Ascentis® Express 90 Å Phenyl-Hexyl (2 μm) HPLC Columns

L × I.D. 5 cm × 2.1 mm UHPLC Column

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About This Item

UNSPSC代码:
41115700
NACRES:
SB.52

product name

Ascentis® Express Phenyl-Hexyl, 2 μm UHPLC Column, 2 μm particle size, L × I.D. 5 cm × 2.1 mm

物料

stainless steel column

质量水平

Agency

suitable for USP L11

产品线

Ascentis®

特点

endcapped

制造商/商品名称

Ascentis®

包装

1 ea of

参数

1000 bar max. pressure (14500 psi)
60 °C temp. range

技术

LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

长度 × 内径

5 cm × 2.1 mm

表面积

120 m2/g

杂质

<5 ppm (metals)

基质

Fused-Core particle platform
superficially porous particle

基质活性基团

dimethylphenylhexyl phase

粒径

2 μm

孔径

90 Å pore size

pH值(酸碱度)

2-9

应用

food and beverages

分离技术

reversed phase

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相关类别

一般描述

Ascentis® Express 2μm Phenyl-Hexyl UHPLC columns are based on a 90 Å Fused-Core® particle design.The Fused-Core particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.4-micron thick porous shell and the small overall particle size of 2-microns. The bonded, endcapped, dimethylphenylhexyl stationary phase of Ascentis Express 2μm Phenyl-Hexyl provides a stable, reversed phase packing with enhanced p-p and mild steric interactions due to the relatively long-chain hexyl linkage to the base silica. Ascentis Express 2μm Phenyl-Hexyl can be used for basic, acidic, or neutral compounds with alternate selectivity from C18.

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法律信息

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

法规信息

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C M Chavez-Eng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1011, 204-214 (2016-01-17)
An ultra-high performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method for the simultaneous determination of (4S,5R)-5-[3,5-bis (trifluoromethyl)phenyl]-3-{[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl] methyl}-4-methyl-1,3-oxazolidin-2-one (anacetrapib, I) and [(13)C5(15)N]-anacetrapib, II in human plasma has been developed to support a clinical study to determine the absolute bioavailability of I.
E Lesellier
Journal of chromatography. A, 1266, 34-42 (2012-11-03)
The recent introduction of new stationary phases for liquid chromatography based on superficially porous particles, called core-shell or fused-core, dramatically improved the separation performances through very high efficiency, due mainly to reduced eddy diffusion. However, few studies have evaluated the
Petr Chocholouš et al.
Talanta, 103, 221-227 (2012-12-04)
Currently, for Sequential Injection Chromatography (SIC), only reversed phase C18 columns have been used for chromatographic separations. This article presents the first use of three different stationary phases: three core-shell particle-packed reversed phase columns in flow systems. The aim of
Ivona Lhotská et al.
Analytical and bioanalytical chemistry, 408(12), 3319-3329 (2016-03-20)
A new fast and sensitive method based on on-line solid-phase extraction on a fused-core precolumn coupled to liquid chromatography with fluorescence detection has been developed for ochratoxin A (OTA) and citrinin (CIT) determination in lager beer samples. Direct injection of
Alex D Batista et al.
Talanta, 133, 142-149 (2014-12-02)
On-line sample pretreatment (clean-up and analyte preconcentration) is for the first time coupled to sequential injection chromatography. The approach combines anion-exchange solid-phase extraction and the highly effective pentafluorophenylpropyl (F5) fused-core particle column for separation of eight sulfonamide antibiotics with similar

相关内容

Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).

小分子特指低分子量化合物(通常小于900道尔顿),分离小分子方法包括高效液相色谱(HPLC)、液相(LC)、气相(GC)、薄层色谱(TLC) 和毛细管电泳(CE)。此外,还可通过磁共振波谱法(NMR)或 质谱法(MS)等方法鉴定小分子。

Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).

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