推荐产品
产品名称
Astec® CHIROBIOTIC® R手性HPLC柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
物料
stainless steel column
质量水平
描述
HPLC column
产品线
Astec®
包装
pkg of 1 ea
制造商/商品名称
Astec®
参数
0-45 °C temperature
241 bar pressure (3500 psi)
技术
HPLC: suitable
LC/MS: suitable
长度 × 内径
25 cm × 4.6 mm
基质
high-purity silica gel particle platform
fully porous particle
基质活性基团
ristocetin A glycopeptide phase
粒径
5 μm
孔径
100 Å
工作pH范围
3.5-6.8
分离技术
chiral
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一般描述
CHIROBIOTIC® R色谱柱以高纯硅胶为基质并以共价键键合了瑞斯托菌素A糖肽，已表现出适用于分离阴离子化合物对映体的特殊性能。CHIROBIOTIC ®R的选择性与有机改性剂密切相关，极其有利于醇类流动相。
CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献
- 键合相：瑞斯西丁A
- pH适用范围：3.5 - 6.8
- 粒子直径：5、10或16 μm
- 孔径：100 Å
CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献
应用
- 乳酸异构体的灵敏分析：Astec® CHIROBIOTIC® R手性HPLC色谱柱在Henry H等的研究中发挥了重要作用，它用于通过高效液相色谱-串联质谱法灵敏测定尿液中的D-乳酸和L-乳酸。该方法对临床诊断极具意义，因柱子可分离其它方法难以区分的相似化合物(Henry H et al., 2012)。
- 环戊烷羧酸和环己烷羧酸的手性分离：Berkecz R等也采用该柱子通过高效液相色谱法手性分离了多种复杂的2-氨基单-和二羟基环戊烷羧酸和2-氨基二羟基环己烷羧酸。体现柱子的多用性以及分离密切相关手性酸的作用，对生化研究和药品开发极具意义(Berkecz R et al., 2009)。
法律信息
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
应用
产品编号
说明
价格
Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 21 (3), 365-373 (2010)
H Henry et al.
Biomedical chromatography : BMC, 26(4), 425-428 (2011-08-16)
D-lactic acid in urine originates mainly from bacterial production in the intestinal tract. Increased D-lactate excretion as observed in patients affected by short bowel syndrome or necrotizing enterocolitis reflects D-lactic overproduction. Therefore, there is a need for a reliable and
P Dehouck et al.
Journal of chromatography. A, 1010(1), 63-74 (2003-09-25)
Erythromycin is a mixture of macrolide antibiotics produced by Saccharopolyspora erythreas during fermentation. A new method for the analysis of erythromycin by liquid chromatography has previously been developed. It makes use of an Astec C18 polymeric column. After validation in
Diane E Halliwell et al.
Scientific data, 4, 170084-170084 (2017-07-12)
Using a scanning near-field optical microscope coupled to an infrared free electron laser (SNOM-IR-FEL) in low-resolution transmission mode, we collected chemical data from whole cervical cells obtained from 5 pre-menopausal, non-pregnant women of reproductive age, and cytologically classified as normal
B DeCruze et al.
Clinical oncology (Royal College of Radiologists (Great Britain)), 11(4), 252-254 (1999-09-04)
Poor prognosis (poorly differentiated and/or deep myometrial invasion) Stage I endometrial cancer can have a relapse rate as high as 50%. Traditionally, most clinical oncologists treat these patients with external beam radiotherapy after surgery but there is no evidence to
实验方案
Rapid, simple, reproducible chiral separation and quantification of L- and D-lactic acid enantiomers using Supelco’s Astec CHIROBIOTIC® R chiral column and tandem MS.
We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.
Chromatograms
application for HPLCapplication for HPLCapplication for HPLCapplication for HPLC展开我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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