推荐产品
产品名称
Astec® CHIROBIOTIC® R手性HPLC柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
物料
stainless steel column
质量水平
描述
HPLC column
产品线
Astec®
包装
pkg of 1 ea
制造商/商品名称
Astec®
参数
0-45 °C temperature
241 bar pressure (3500 psi)
技术
HPLC: suitable
LC/MS: suitable
长度 × 内径
25 cm × 4.6 mm
基质
high-purity silica gel particle platform
fully porous particle
基质活性基团
ristocetin A glycopeptide phase
粒径
5 μm
孔径
100 Å
工作pH范围
3.5-6.8
分离技术
chiral
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一般描述
CHIROBIOTIC® R色谱柱以高纯硅胶为基质并以共价键键合了瑞斯托菌素A糖肽，已表现出适用于分离阴离子化合物对映体的特殊性能。CHIROBIOTIC ®R的选择性与有机改性剂密切相关，极其有利于醇类流动相。
CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献
- 键合相：瑞斯西丁A
- pH适用范围：3.5 - 6.8
- 粒子直径：5、10或16 μm
- 孔径：100 Å
CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献
应用
- 乳酸异构体的灵敏分析：Astec® CHIROBIOTIC® R手性HPLC色谱柱在Henry H等的研究中发挥了重要作用，它用于通过高效液相色谱-串联质谱法灵敏测定尿液中的D-乳酸和L-乳酸。该方法对临床诊断极具意义，因柱子可分离其它方法难以区分的相似化合物(Henry H et al., 2012)。
- 环戊烷羧酸和环己烷羧酸的手性分离：Berkecz R等也采用该柱子通过高效液相色谱法手性分离了多种复杂的2-氨基单-和二羟基环戊烷羧酸和2-氨基二羟基环己烷羧酸。体现柱子的多用性以及分离密切相关手性酸的作用，对生化研究和药品开发极具意义(Berkecz R et al., 2009)。
法律信息
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
应用
产品编号
说明
价格
Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 21 (3), 365-373 (2010)
B DeCruze et al.
Clinical oncology (Royal College of Radiologists (Great Britain)), 11(4), 252-254 (1999-09-04)
Poor prognosis (poorly differentiated and/or deep myometrial invasion) Stage I endometrial cancer can have a relapse rate as high as 50%. Traditionally, most clinical oncologists treat these patients with external beam radiotherapy after surgery but there is no evidence to
Sébastien Canneaux et al.
The journal of physical chemistry. A, 114(34), 9270-9288 (2010-08-03)
The rate constants of the reactions of iodine atoms with H(2), H(2)O, HI, and OH have been estimated using 39, 21, 13, and 39 different levels of theory, respectively, and have been compared to the available literature values over the
Ting Zhou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1002, 218-227 (2015-09-06)
The chiral inversion has been a concerned issue during the research and development of a chiral drug. In this study, a sensitive chiral liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for determination of salbutamol enantiomers in human plasma and
Diane E Halliwell et al.
Scientific data, 4, 170084-170084 (2017-07-12)
Using a scanning near-field optical microscope coupled to an infrared free electron laser (SNOM-IR-FEL) in low-resolution transmission mode, we collected chemical data from whole cervical cells obtained from 5 pre-menopausal, non-pregnant women of reproductive age, and cytologically classified as normal
实验方案
Rapid, simple, reproducible chiral separation and quantification of L- and D-lactic acid enantiomers using Supelco’s Astec CHIROBIOTIC® R chiral column and tandem MS.
We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.
Chromatograms
application for HPLCapplication for HPLCapplication for HPLCapplication for HPLC展开我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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