类型
Type IV
质量水平
检测方案
≥93.0% (HPLC)
溶解性
H2O: soluble 25 mg of UTP in 0.5 ml of solvent, clear, colorless
储存温度
−20°C
SMILES字符串
[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
InChI
1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
InChI key
MMJGIWFJVDOPJF-LLWADOMFSA-K
正在寻找类似产品? 访问 产品对比指南
相关类别
应用
UTP 已被用作 P2 受体激活剂,研究其对 MC3T3-E1 和 UMR-106 细胞质子外流的影响 。还研究了 UTP 与盐酸阿米洛利雾化溶液联合治疗囊性纤维化 。
尿苷 5′-三磷酸盐曾用于一项研究显示氟西汀 (FLX) 通过增加腺苷 5′ 的胶质传递而介导其抗抑郁作用-三磷酸盐 (ATP)。
生化/生理作用
尿苷-5′-三磷酸盐 (UTP) 是核酸的细胞溶质核苷酸成分。作为细胞外间隙中的信号分子。尿苷-5′-三磷酸盐 (UTP) 参与神经系统的多种病理生理反应。UTP 在再生过程中也起主要角色。
P2Y 受体激动剂。
包装
无底玻璃瓶。内含物装在插入的融合锥内。
制备说明
25 mg 尿苷 5'-三磷酸三钠盐 (UTP Na 3 ) 水合物可溶于 0.5 mL 水中,并产生澄清、无色溶液。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes
EBioMedicine, 372(2), 255-265 (2018)
Uridine-5?-Triphosphate Partially Blocks Differentiation Signals and Favors a more Repair State in Cultured rat Schwann Cells
Neuroscience, 372(2), 255-265 (2018)
Journal of pharmaceutical sciences, 93(9), 2399-2406 (2004-08-06)
Combination therapy using nebulized amiloride hydrochloride and uridine-5'-triphosphate (UTP) trisodium salt aerosols has been investigated for the treatment of cystic fibrosis (CF). Amiloride in aqueous solution precipitates in the presence of UTP, reducing drug concentrations. Interactions between these drugs and
Intralesional uridine-5?-triphosphate (UTP) treatment induced resistance to Leishmania amazonensis infection by boosting Th 1 immune responses and reactive oxygen species production
Purinergic Signaling, 14(2), 201-211 (2018)
Cell reports, 37(4), 109882-109882 (2021-10-16)
Remdesivir (RDV), a nucleotide analog with broad-spectrum features, has exhibited effectiveness in COVID-19 treatment. However, the precise working mechanism of RDV when targeting the viral RNA-dependent RNA polymerase (RdRP) has not been fully elucidated. Here, we solve a 3.0-Å structure
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门