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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
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主要文件

U1752

Sigma-Aldrich

尿苷5-单磷酸

≥98%

别名:

U 5′-P, UMP, 尿苷酸

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1 G
CN¥2,578.58

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国内现货,预计发货时间April 27, 2025详情


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1 G
CN¥2,578.58

About This Item

经验公式(希尔记法):
C9H13N2O9P
CAS号:
分子量:
324.18
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

CN¥2,578.58


国内现货,预计发货时间April 27, 2025详情


获取大包装报价

生物来源

natural (organic)

质量水平

方案

≥98%

表单

powder

溶解性

H2O: soluble 50 mg/mL, clear, colorless

储存温度

−20°C

SMILES字符串

OC1C(O)C(OC1COP(O)(O)=O)N2C=CC(=O)NC2=O

InChI

1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)

InChI key

DJJCXFVJDGTHFX-UHFFFAOYSA-N

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U6375A2252D6375
biological source

natural (organic)

biological source

(chemical)

biological source

yeast

biological source

synthetic (organic)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

assay

≥98%

assay

≥99%

assay

≥97%

assay

98-100%

solubility

H2O: soluble 50 mg/mL, clear, colorless

solubility

-

solubility

1 M NH4OH: soluble 50 mg/mL, clear, colorless, H2O: soluble (with addition of mild alkali)

solubility

1 N NH4OH: 50 mg/mL, clear, colorless

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

一般描述

尿苷5′-单磷酸盐可用作所有嘧啶核苷酸的前体。[1]

应用

5′-尿苷单磷酸可作为等渗溶液伤口屏障重建实验中E3等渗液的组分,研究其对等渗液中基底细胞反应或上皮细胞向伤口迁移的影响。[2]

生化/生理作用

5′-尿苷单磷酸(UMP)是RNA中的一种核苷酸单体,由核碱基尿嘧啶、核糖和磷酸组成。UMP作为膳食补充剂可增强神经递质释放和神经突生长,也可促进成年大鼠膜磷脂的生产。[3]对成年沙鼠联合喂饲DHA和UMP后,树突棘和神经元膜合成增加。表明UMP可用于突触缺失引起的认知障碍治疗。[4]

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

  • 技术规格说明书

  • 历史批次信息供参考:

    分析证书(COA)

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    Chaitanya V Mungi et al.
    Life (Basel, Switzerland), 9(3) (2019-07-07)
    Polymerization of nucleotides under prebiotically plausible conditions has been a focus of several origins of life studies. Non-activated nucleotides have been shown to undergo polymerization under geothermal conditions when subjected to dry-wet cycles. They do so by a mechanism similar
    Xiaozhen Chen et al.
    Journal of pharmaceutical and biomedical analysis, 174, 432-440 (2019-06-21)
    A novel, simple, and efficacious analytical method for determining of nucleotides in Anoectochilus roxburghii (Wall.) Lindl (A. roxburghii) was developed. Magnetic dispersive solid-phase micro-extraction (MDSPME) combined with high-performance liquid chromatography was applied for extraction and determination of three nucleotides, such
    Lei Wang et al.
    Journal of molecular neuroscience : MN, 27(1), 137-145 (2005-08-02)
    Membrane phospholipids like phosphatidylcholine (PC) are required for cellular growth and repair, and specifically for synaptic function. PC synthesis is controlled by cellular levels of its precursor, cytidine-5'-diphosphate choline (CDP-choline), which is produced from cytidine triphosphate (CTP) and phosphocholine. In
    Regulation of uridylic acid biosynthesis in the cyanobacterium Anabaena variabilis.
    Currier TC and Wolk CP
    Journal of Bacteriology, 136(2), 682-687 (1978)
    Toshimasa Sakamoto et al.
    Brain research, 1182, 50-59 (2007-10-24)
    Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid, is an essential component of membrane phosphatides and has been implicated in cognitive functions. Low levels of circulating or brain DHA are associated with various neurocognitive disorders including Alzheimer's disease (AD), while

    实验方案

    ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

    HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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