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安全信息

TRUEPVAF

Sigma-Aldrich

TrueGel3D聚合物

modified for fast gelling (FAST-PVA)

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About This Item

UNSPSC代码:
12352207
NACRES:
NA.71

生物来源

synthetic

技术

cell attachment: suitable

运输

dry ice

储存温度

−70°C

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一般描述

PVA polymers are functionalized with thiol-reactive maleimide groups, which react rapidly with thiol groups of crosslinkers to form hydrogels in few seconds. The thiol-reactive maleimide groups are also compatible to conjugate polymers with bioactive factors. The thioglycerol is used to maintain hydrogel strength and also as a control to compare cellular behavior in peptide-modified versus unmodified hydrogels. The buffers (pH7.2 and pH 5.5) are used to control pH and osmotic conditions to optimize time for gelation.

应用

FAST-PVA polymer is used with crosslinkers (CD/PEG crosslinkers) to establish stable hydrogels.

特点和优势

  • Contains synthetic polymer (PVA) functionalized with maleimide groups for quick gelation
  • Non degradable polymer

组分

TRUEPVAF contains FAST-PVA solution in phosphate buffer, TrueGel3D thioglycerol and water.

注意

Avoid frequent freeze-thaw cycles and store FAST-PVA polymer in small portions.

象形图

Corrosion
GHS05

警示用语：

Warning

危险声明

H290

预防措施声明

P234 - P390

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0001615176

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商品

True Gel3D™ Hydrogel Troubleshooting

Troubleshoot TrueGel3D™ hydrogel formation and cell viability issues with RGD-degradable polymer and CD cell-degradable crosslinker.

TrueGel3D™ Hydrogel for 3D Cell Culture

TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions

3D细胞培养水凝胶_细胞培养_TrueGel3D™水凝胶-默克生命科学

TrueGel3D™细胞培养水凝胶是一种由混合聚合物与交联剂混合而成的生化成分限定的水凝胶。与其他基于动物细胞生物提取物（例如小鼠EHS肿瘤细胞）的水凝胶相比，TrueGel3D™细胞培养水凝胶不含任何可能会干扰或造成实验污染的动物源成分。

实验方案

Advanced Protocol: How to Customize your TrueGel3D™ Hydrogel

An advanced protocol is available for TrueGel 3D kits for 3D cell culture for peptides concentration or stiffness optimisation

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