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Merck
CN

TRUEPEG

Sigma-Aldrich

TrueGel3D Crosslinker

PEG non cell-degradable crosslinker

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About This Item

UNSPSC代码:
12352207
NACRES:
NA.71

运输

dry ice

储存温度

−20°C

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一般描述

PEG-Link is comprised of polyethylene glycol and thiol (SH) groups at each end. The thiol groups form stable thioether bond with thiol-reactive groups of the polymers (Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran), which results in stable hydrogel. The matrix metalloproteases secreted by cells cannot cleave PEG crosslinker.

应用

TRUEPEG is used to crosslink PVA and dextran polymers to generate stable hydrogel.

特点和优势

Non-MMP degradable.

组分

TRUEPEG contains PEG non cell-degradable crosslinker lyophilized and water.

注意

Avoid prolong exposure of PEG non cell-degradable crosslinker to air.

储存分类代码

10 - Combustible liquids

WGK

WGK 3

法规信息

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分析证书(COA)

Lot/Batch Number

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商品

Troubleshoot TrueGel3D™ hydrogel formation and cell viability issues with RGD-degradable polymer and CD cell-degradable crosslinker.

TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions

TrueGel3D™细胞培养水凝胶是一种由混合聚合物与交联剂混合而成的生化成分限定的水凝胶。与其他基于动物细胞生物提取物(例如小鼠EHS肿瘤细胞)的水凝胶相比,TrueGel3D™细胞培养水凝胶不含任何可能会干扰或造成实验污染的动物源成分。

实验方案

TrueGel3D hydrogel enables cell encapsulation for 3D culture, mimicking native tissue environment with chemically defined properties.

TrueGel3D™ is a chemically defined hydrogel for 3D cell growth, facilitating microchannel filling with slow gelation.

An advanced protocol is available for TrueGel 3D kits for 3D cell culture for peptides concentration or stiffness optimisation

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