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Merck
CN

T7515

牛磺石胆酸钠

别名:

3α-羟基-5β-胆烷-24-羧酸-N-（2-磺乙基）酰胺, 牛磺石胆酸 钠盐

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关于此项目

线性分子式:
C26H44NO5SNa
化学文摘社编号:
6042-32-6
分子量:
505.69
UNSPSC Code:
12161900
PubChem Substance ID:
24900457
NACRES:
NA.25

主要文件

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SMILES string

C[C@H](CCC(NCCS(=O)(O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na]

InChI

1S/C26H45NO5S.Na.H/c1-17(4-9-24(29)27-14-15-33(30,31)32)21-7-8-22-20-6-5-18-16-19(28)10-12-25(18,2)23(20)11-13-26(21,22)3;;/h17-23,28H,4-16H2,1-3H3,(H,27,29)(H,30,31,32);;/t17-,18-,19-,20+,21-,22+,23+,25+,26-;;/m1../s1

InChI key

CMXYYIRKQPXCIE-RLHFEMFKSA-N

description

anionic

assay

≥97.0% (TLC)

mol wt

505.69 g/mol

application(s)

detection

Quality Level

200

相关类别

General description

牛磺胆酸钠是一种具有洗涤剂特性的胆汁盐，该特性使其能够溶解不溶性脂质。

Application

牛磺胆酸钠已被用于评估石油烃残留物的胃肠道吸附的控制因素。 它还被用于研究诱导胆汁淤积的大鼠中Na+、K+-腺苷三磷酸酶（Na+、K+-ATP酶）活性的降低。

wgk

WGK 3

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000373029
0000334511
0000310778
0000334511
0000310778

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Xuejun Zhang et al.
The journal of physical chemistry. B, 115(49), 14445-14449 (2011-11-15)
Stimuli-responsive organic tubes are an attractive supramolecular assembly which has potential applications as a controlled release vehicle. We synthesize a smart organic tube by the coassembly of lithocholic acid (LCA) and taurolithocholic acid (TLCA) in aqueous solution. The coassembled LCA/TLCA
Sohail Z Husain et al.
American journal of physiology. Gastrointestinal and liver physiology, 302(12), G1423-G1433 (2012-04-21)
Biliary pancreatitis is the most common etiology for acute pancreatitis, yet its pathophysiological mechanism remains unclear. Ca(2+) signals generated within the pancreatic acinar cell initiate the early phase of pancreatitis, and bile acids can elicit anomalous acinar cell intracellular Ca(2+)
J Reichen et al.
Experientia, 35(9), 1186-1188 (1979-09-15)
Na +, K + -adenosinetriphosphatase (Na +, K + -ATPase) activity was decreased in liver plasma membranes from rats in which cholestasis had been induced by i.v. administration of sodium taurolithocholate (5 mumoles/100 g b. wt). Incubation of liver plasma
Hoi-Ying N Holman et al.
Environmental science & technology, 36(6), 1281-1286 (2002-04-12)
Petroleum hydrocarbon residues in weathered soils may pose risks to humans through the ingestion pathway. To understand the factors controlling their gastrointestinal (GI) absorption, a newly developed experimental extraction protocol was used to model the GI solubility of total petroleum
Barbara Döring et al.
Current topics in membranes, 70, 105-168 (2012-11-28)
The SLC10 family represents seven genes containing 1-12 exons that encode proteins in humans with sequence lengths of 348-477 amino acids. Although termed solute carriers (SLCs), only three out of seven (i.e. SLC10A1, SLC10A2, and SLC10A6) show sodium-dependent uptake of
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