T4626
Nα-p甲苯磺酰基-L-精氨酸甲酯 盐酸盐
≥98% (TLC), suitable for ligand binding assays
别名:
TAME 盐酸盐
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线性分子式:
H2NC(=NH)NH(CH2)3CH(NHSO2C6H4CH3)CO2CH3 · HCl
化学文摘社编号:
分子量:
378.87
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352103
EC Number:
217-235-1
MDL number:
Beilstein/REAXYS Number:
3922357
产品名称
Nα-p甲苯磺酰基-L-精氨酸甲酯 盐酸盐,
InChI key
JIQFFACVQXXHMY-YDALLXLXSA-N
InChI
1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1
SMILES string
Cl.COC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc(C)cc1
assay
≥98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white
mp
145-147 (lit.)
storage temp.
−20°C
Quality Level
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Application
Nα-对甲苯磺酰基-L-精氨酸甲酯盐酸盐已被用作酯水解底物，用于评估中肠提取物中胰蛋白酶样活性。它也已被用作测定胰酶和人肠样品中胰蛋白酶活性的底物。
Biochem/physiol Actions
Nα-对甲苯磺酰基-L-精氨酸甲酯（TAME）与后期促进复合物（APC）结合并阻止其被Cdc20和Cdh1激活。
General description
胰蛋白酶、凝血酶、纤溶酶和其他蛋白酶的底物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Character of a wheat amylase inhibitor preparation and effects on fasting human pancreaticobiliary secretions and hormones
Choudhury A, et al.
Gastroenterology, 111(5), 1313-1320 (1996)
In vitro digestibility of goat milk and kefir with a new standardised static digestion method (INFOGEST cost action) and bioactivities of the resultant peptides
El SN, et al.
Food & Function, 6(7), 2322-2330 (2015)
Sappasith Klomklao et al.
Journal of agricultural and food chemistry, 54(15), 5617-5622 (2006-07-20)
Trypsin from tongol tuna (Thunnus tonggol) spleen was purified to 402-fold by ammonium sulfate precipitation, followed by a series of chromatographic separations. The molecular mass of trypsin was estimated to be 24 kDa by size-exclusion chromatography and sodium dodecyl sulfate-polyacrylamide
A modified spectrophotometric determination of chymotrypsin, trypsin, and thrombin.
B C HUMMEL
Canadian journal of biochemistry and physiology, 37, 1393-1399 (1959-12-01)
Jie Wang et al.
Frontiers in microbiology, 12, 708990-708990 (2021-09-24)
Koinobiont endoparasitoid wasps whose larvae develop inside a host insect alter several important facets of host physiology, potentially causing cascading effects across multiple trophic levels. For instance, the hijacking of the host immune responses may have effects on how insects
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