product name
Nα-p甲苯磺酰基-L-精氨酸甲酯 盐酸盐,
检测方案
≥98% (TLC)
质量水平
形式
powder
技术
ligand binding assay: suitable
颜色
white
mp
145-147 (lit.)
储存温度
−20°C
SMILES字符串
Cl.COC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc(C)cc1
InChI
1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1
InChI key
JIQFFACVQXXHMY-YDALLXLXSA-N
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应用
Nα-对甲苯磺酰基-L-精氨酸甲酯盐酸盐已被用作酯水解底物,用于评估中肠提取物中胰蛋白酶样活性。它也已被用作测定胰酶和人肠样品中胰蛋白酶活性的底物。
生化/生理作用
Nα-对甲苯磺酰基-L-精氨酸甲酯(TAME)与后期促进复合物(APC)结合并阻止其被Cdc20和Cdh1激活。
底物
胰蛋白酶、凝血酶、纤溶酶和其他蛋白酶的底物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Microtubule inhibitors are important cancer drugs that induce mitotic arrest by activating the spindle assembly checkpoint (SAC), which, in turn, inhibits the ubiquitin ligase activity of the anaphase-promoting complex (APC). Here, we report a small molecule, tosyl-L-arginine methyl ester (TAME)
In vitro digestibility of goat milk and kefir with a new standardised static digestion method (INFOGEST cost action) and bioactivities of the resultant peptides
Food & Function, 6(7), 2322-2330 (2015)
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Gastroenterology, 111(5), 1313-1320 (1996)
Frontiers in physiology, 6, 95-95 (2015-04-16)
Pieris brassicae L. is a serious pest of cultivated crucifers in several parts of the world. Larvae of P. brassicae also feed prolifically on garden nasturtium (Tropaeolum majus L., of the family Tropaeolaceae). Proteolytic digestion was studied in larvae feeding
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