推荐产品
生物来源
rabbit
质量水平
偶联物
TRITC conjugate
抗体形式
IgG fraction of antiserum
抗体产品类型
secondary antibodies
克隆
polyclonal
表单
buffered aqueous solution
储存条件
protect from light
技术
direct immunofluorescence: 1:64
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200
储存温度
−20°C
靶向翻译后修饰
unmodified
一般描述
免疫球蛋白(Ig)属于免疫球蛋白超家族。存在有五种不同类型的免疫球蛋白。每种免疫球蛋白包含有两条重链(H)和两条轻链(L),它们通过二硫键连接。每条轻链包含一个可变的N-端区域和一个恒定C-端区域。重链包含有一个可变的N-端区域以及三个或四个恒定的(CH1-CH4)C-末端区域。IgG是在人血清中丰度较高的免疫球蛋白。IgG 的四种类型分别为IgG1、IgG2、IgG3和IgG4。
特异性
抗-小鼠IgG(全分子)-TRITC抗体对小鼠IgG具有特异性。
免疫原
正常小鼠血清
应用
抗小鼠IgG(全分子)-TRITC抗体适用于直接免疫荧光(1:64)、免疫组化(福尔马林固定、石蜡包埋切片1:200稀释)、Ouchterlony双扩散和电泳技术。
生化/生理作用
免疫球蛋白G(IgG)是一种糖蛋白抗体,可调节免疫反应(如吞噬作用),也可影响自身免疫疾病的进程。小鼠IgG具有四种不同的亚型,即IgG1、IgG2a、IgG2b和IgG3。IgG1可调节小鼠的补体结合。
木瓜蛋白酶对IgG的消化导致产生片段抗原结合(Fab),该片段包含一个完整的L链和H链的可变区和CH1区。IgG的胃蛋白酶消化产生可结晶片段(fc),包含H链恒定区。
外形
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
从最新的版本中选择一种:
分析证书(COA)
eLife, 5 (2016-12-03)
Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation. Our data show that nuclei in differentiated bovine
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Spinal bulbar muscular atrophy (SBMA) is a progressive, late onset neuromuscular disease causing motor dysfunction in men. While the morphology of the neuromuscular junction (NMJ) is typically affected by neuromuscular disease, whether NMJs in SBMA are similarly affected by disease
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(22), 7481-7487 (2008-11-18)
We seek to establish a genetic test to identify lung cancer using cells obtained through computed tomography-guided fine needle aspiration (FNA). We selected regions of frequent copy number gains in chromosomes 1q32, 3q26, 5p15, and 8q24 in non-small cell lung
The European journal of neuroscience, 13(7), 1339-1348 (2001-04-12)
Corticotropin-releasing factor (CRF), a neuropeptide of 41 amino acids, acts as the major physiological regulator of the basal and stress-induced release of corticotropin (ACTH), beta-endorphin and other proopiomelanocortin-derived peptides from the anterior pituitary gland. In addition to its endocrine activity
Journal of applied physiology (Bethesda, Md. : 1985), 81(6), 2658-2665 (1996-12-01)
The aim of this study was to analyze the effects of treadmill training (2 h/day, 5 days/wk, 30 m/min, 7% grade for 5 wk) on the expression of myosin heavy chain (MHC) isoforms during and after regeneration of a fast-twitch
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