T1378

Sigma 7-9®^®

Name: Sigma 7-9®<SUP>®</SUP>
Brand: SIGMA

≥99% (titration), crystalline, Sigma 7-9^®

别名:

Trizma ^® 碱, 2-氨基-2-(羟甲基)-1,3-丙二醇, THAM, Tris 碱, 三羟甲基氨基甲烷, 氨基丁三醇

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线性分子式:

NH₂C(CH₂OH)₃

化学文摘社编号:

77-86-1

分子量:

121.14

NACRES:

NA.25

PubChem Substance ID:

24899961

UNSPSC Code:

12352104

EC Number:

201-064-4

MDL number:

MFCD00004679

Beilstein/REAXYS Number:

741883

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产品名称

Sigma 7-9®^®, ≥99% (titration), powder or crystals

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

SMILES string

NC(CO)(CO)CO

description

aminopeptidase substrate

assay

≥99% (titration)

form

powder or crystals

storage condition

dry at room temperature

technique(s)

ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable

impurities

≤0.5% water (Karl Fischer)

color

white to off-white

pH

10.5-12

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)

mp

167-172 °C (lit.)

solubility

water: 0.667 g/mL, clear, colorless to faintly yellow

absorption

≤0.4 at 290 at 40%

application(s)

clinical research
diagnostic assay manufacturing
life science and biopharma
sample preparation

Quality Level

200

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Application

Sigma 7-9^®已用于：

作为样品制备的缓冲液，用于涉及酶联免疫吸附测定(ELISA)的研究
作为样品制备缓冲液，用于免疫组织化学和免疫荧光相关研究

Features and Benefits

适用于生物和生化研究
在 pH 7-9 (25 °C)范围内有效缓冲，pKa 为 8.1 (25 °C)

General description

Sigma 7-9^® 也称为Trizma 碱或三（羟甲基）氨基甲烷，是一种多功能生物缓冲液，可用于多种应用，例如蛋白质冷冻、电泳以及 TAE 和 TBE 等缓冲溶液的制备。Tris 的 pKa 为 8.06，对于在生物体典型生理 pH 范围（pH 7.0-9.0）内工作的实验室特别有价值。它还通常与其他缓冲剂联合用于精确调节溶液的 pH 值。

此外，Tris 有助于增强细胞膜的渗透性。这种化合物在其用于制备与生物体液相容的缓冲液，作为标准 pH 溶液，促进乳酸脱氢酶测定、原位杂交和细胞蛋白质提取等实验方案的实验室中不可或缺。

Other Notes

如需了解生化试剂系列的更多信息，请填写此表。

所有缓冲液的 pH 值都取决于温度和浓度。Tris 缓冲液，温度每降低 1°C，pH 值增加约 0.03 个单位，每稀释十倍 pH 值降低0.03-0.05 个单位。
对于精确的应用，使用经过精心校准的 pH 计和玻璃/甘汞组合电极。

Legal Information

Sigma 7-9 is a registered trademark of Merck KGaA, Darmstadt, Germany

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Sigma 7-9®®

≥99% (titration), crystalline, Sigma 7-9®

选择尺寸

关于此项目

主要文件

属性

产品名称

InChI key

InChI

SMILES string

description

assay

form

storage condition

technique(s)

impurities

color

pH

useful pH range

pKa (25 °C)

bp

mp

solubility

absorption

application(s)

Quality Level

相关类别

说明

Application

Features and Benefits

General description

Other Notes

Legal Information

安全信息

存储类别

wgk

ppe

文件

分析证书(COA)

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Sigma 7-9®^®

≥99% (titration), crystalline, Sigma 7-9^®