T0682
牛磺猪去氧胆酸钠 水合物
≥98%
别名:
牛磺猪去氧胆酸 钠盐 水合物
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关于此项目
线性分子式:
C26H44NO6SNa · xH2O
化学文摘社编号:
分子量:
521.69 (anhydrous basis)
PubChem Substance ID:
NACRES:
NA.25
UNSPSC Code:
12161900
MDL number:
产品名称
牛磺猪去氧胆酸钠 水合物, ≥98%
InChI key
MJKUJELEPWZEGU-IGEKTTBWSA-M
SMILES string
O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C26H45NO6S.Na.H2O/c1-16(4-7-24(30)27-12-13-34(31,32)33)19-5-6-20-18-15-23(29)22-14-17(28)8-10-26(22,3)21(18)9-11-25(19,20)2;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18+,19-,20+,21+,22+,23+,25-,26-;;/m1../s1
description
anionic
assay
≥98%
mol wt
521.69 g/mol (anhydrous basis)
application(s)
detection
Quality Level
Application
牛磺猪去氧胆酸钠水合物已用于一项研究，以评估呋喃处理大鼠肝脏中细胞毒性、再生性细胞增殖和继发性氧化 DNA 损伤的剂量响应数据。 它也被用于一项研究，以探讨使用固定化人工膜 HPLC 柱预测胆盐-膜相互作用。
General description
牛磺猪去氧胆酸钠水合物是牛磺酸酰胺化胆盐，可作为阴离子洗涤剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
K J Van Erpecum et al.
European journal of clinical investigation, 26(7), 602-608 (1996-07-01)
Precipitation of cholesterol crystals is an essential step in gallstone formation. In the present study we found much faster and more extensive precipitation of various cholesterol crystal shapes in whole model biles containing the hydrophobic bile salt taurodeoxycholate than in
Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat.
A Roda et al.
Hepatology (Baltimore, Md.), 27(2), 520-525 (1998-02-14)
The prevention of the hepatotoxic effects produced by intravenous infusion of taurochenodeoxycholic acid (TCDCA) by coinfusion with taurohyodeoxycholic acid (THDCA) was evaluated in bile fistula rats; the hepatoprotective effects of the latter were also compared with those of tauroursodeoxycholic acid
A S Tripodi et al.
Arzneimittel-Forschung, 43(8), 897-903 (1993-08-01)
The mutagenicity of a new biliary acid, taurohyodeoxycholic acid (THDCA, Io, Praxis, CAS 2958-04-5), was assayed by using 5 different tests. The Ames test (reverse mutation assay on Salmonella typhimurium) and the DNA damage and repair test (in Saccharomyces cerevisiae)
A S Tripodi et al.
Arzneimittel-Forschung, 43(8), 877-880 (1993-08-01)
In this study we investigated the anticholelithogenic and choleretic activities and the general pharmacological action of taurohyodeoxycholic acid (THDCA, Io, Praxis, CAS 2958-04-5), a new biliary acid advocated for use as anticholelithogenic agent. THDCA had no significant activity on the
F Lanzarotto et al.
Scandinavian journal of gastroenterology, 36(9), 981-986 (2001-08-28)
Tauro-hyodeoxycholic acid is a hydrophilic bile acid of potential interest for treating cholestatic liver diseases. Bile acid pool is enriched with this bile acid during acute administration in patients with interrupted enterohepatic circulation. The aim of our study was to
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