T0251
胸腺嘧啶核苷5′-三磷酸 钠盐
≥96%
别名:
TTP, dTTP
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关于此项目
经验公式（希尔记法）:
C10H16N2O14P3Na
化学文摘社编号:
分子量:
504.15
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
产品名称
胸腺嘧啶核苷5′-三磷酸 钠盐, ≥96%
SMILES string
[NaH].[P](=O)(O[P](=O)(OCC1OC(CC1O)N2C=C(C(=O)NC2=O)C)O)(O[P](=O)(O)O)O
InChI
1S/C10H17N2O14P3.Na.H/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);;
InChI key
KAELIXTVSANDSE-UHFFFAOYSA-N
assay
≥96%
shipped in
dry ice
storage temp.
−20°C
Quality Level
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Application
5′胸苷三磷酸钠盐可用于：
- 基于多适体氧化石墨烯纳米片复合物的双适体淬灭能力实验和多核苷酸检测
- 研究大肠杆菌中心代谢中的蛋白质-代谢物相互作用
- 以AM-toxin为引物，合成聚合物链式反应(PCR)产物
胸腺嘧啶核苷 5′-三磷酸（dTTP）是四种天然脱氧核苷酸之一，与脱氧腺苷 5′-三磷酸（dATP）、脱氧鸟苷 5′-三磷酸（dGTP）和脱氧胞嘧啶 5′-三磷酸（dCTP）一起通过DNA聚合酶和逆转录酶用于脱氧核糖核酸的生物合成。脱氧-TTP 也可用作研究胸苷-三磷酸酶（EC 3.6.1.39）和其他 dTTP 水解活性的特异性和动力学的底物。
Biochem/physiol Actions
胸苷三磷酸是DNA的结构单元。可作为其他核苷酸代谢的异构调节蛋白。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Chien-Sung Tsai et al.
American journal of translational research, 8(12), 5338-5353 (2017-01-13)
Eotaxin-2 is a potent chemoattractant. High concentration of eotaxin-2 triggers the inflammation and tumor metastasis. Inhibition of eotaxin-2 may protect experimental atherogenesis although the mechanism is still unclear. Toll-like receptor 4 (TLR4) plays a major role mediating vascular inflammation, which
Felicitas Rataj et al.
Molecular biology of the cell, 27(24), 3841-3854 (2016-10-07)
TPA-inducible sequence 11b/butyrate response factor 1 (TIS11b/BRF1) belongs to the tristetraprolin (TTP) family of zinc-finger proteins, which bind to mRNAs containing AU-rich elements in their 3'-untranslated region and target them for degradation. Regulation of TTP family function through phosphorylation by
Ji Eun Park et al.
PloS one, 12(7), e0181933-e0181933 (2017-07-22)
To determine if perfusion in surgical cavity wall enhancement (SCWE) obtained in early post-treatment MR imaging can stratify time-to-progression (TTP) in glioblastoma. This study enrolled 60 glioblastoma patients with more than 5-mm-thick SCWEs as detected on contrast-enhanced MR imaging after
Zhuangsheng Liu et al.
Journal of magnetic resonance imaging : JMRI, 50(3), 847-857 (2019-02-19)
Lymphovascular invasion (LVI) status facilitates the selection of optimal therapeutic strategy for breast cancer patients, but in clinical practice LVI status is determined in pathological specimens after resection. To explore the use of dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI)-based radiomics
Christina Jensen et al.
Scientific reports, 7(1), 2830-2830 (2017-06-08)
In the absence of a validated correlate of protection or robust animal models for human tuberculosis, Mycobacterial growth inhibition assays (MGIAs) aim to assess vaccines ability to inhibit mycobacterial growth in-vitro. We optimised a reproducible murine splenocyte MGIA based on
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