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Merck
CN
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文件

安全信息

SRP0453

Sigma-Aldrich

BRD2 (339-459) GST tag human

recombinant, expressed in E. coli, ≥86% (SDS-PAGE)

别名:

NAT

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in E. coli

检测方案

≥86% (SDS-PAGE)

形式

aqueous solution

分子量

41.4 kDa

包装

pkg of 100 μg

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... BRD2(6046)

一般描述

Human Bromodomain containing 2, also known as BRD2, RING3 or RNF3 (GenBank Accession No. NM_005104) amino-acids 65 – 187 with N-terminal GST-tag, MW = 41.4 kDa, expressed in an E. coli expression system.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Takashi Umehara et al.
FEBS letters, 584(18), 3901-3908 (2010-08-17)
The BET family proteins recognize acetylated chromatin through their two bromodomains, acting as transcriptional activators or tethering viral genomes to the mitotic chromosomes of their host. The structural mechanism for how the N-terminal bromodomain of human BRD2 (BRD2-BD1) deciphers the
Enyuan Shang et al.
Journal of cellular biochemistry, 112(10), 2784-2793 (2011-05-25)
The human BRD2 gene has been linked and associated with a form of common epilepsy and electroencephalographic abnormalities. Disruption of Brd2 in the mouse revealed that it is essential for embryonic neural development and that viable Brd2(+/-) heterozygotes show both

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