生物来源
human
重组
expressed in E. coli
检测方案
≥90% (SDS-PAGE)
形式
aqueous solution
分子量
15.5 kDa
包装
pkg of 100 μg
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... BRD2(6046)
一般描述
Human Bromodomain containing 2, also known as BRD2, RING3 or RNF3 (GenBank Accession No. NM_005104) amino-acids 65 – 187 with N-terminal His-tag, MW = 15.5 kDa, expressed in an E. coli expression system.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Takashi Umehara et al.
FEBS letters, 584(18), 3901-3908 (2010-08-17)
The BET family proteins recognize acetylated chromatin through their two bromodomains, acting as transcriptional activators or tethering viral genomes to the mitotic chromosomes of their host. The structural mechanism for how the N-terminal bromodomain of human BRD2 (BRD2-BD1) deciphers the
Enyuan Shang et al.
Journal of cellular biochemistry, 112(10), 2784-2793 (2011-05-25)
The human BRD2 gene has been linked and associated with a form of common epilepsy and electroencephalographic abnormalities. Disruption of Brd2 in the mouse revealed that it is essential for embryonic neural development and that viable Brd2(+/-) heterozygotes show both
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