生物来源
human
重组
expressed in baculovirus infected Sf9 cells
检测方案
≥72% (SDS-PAGE)
形式
aqueous solution
分子量
99.8 kDa
包装
pkg of 20 μg
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... UBE3A(7337)
一般描述
Human UBE3A (var1) (GenBank Accession No. NM_130838) amino acids 2-end with N-terminal His-FLAG-tag, MW=99.8 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
应用
Useful in conjunction with E1and E2 for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
外形
Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 250mM imidazole, 20% Glycerol and 3mM DTT.
警示用语：
Danger
危险声明
危险分类
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Eui-Man Jung et al.
International journal of molecular medicine, 28(5), 697-704 (2011-08-13)
Some human embryonic stem cell lines have shown genomic instabilities over long-term culture. To study the controversial origin of the SCNT-hES-1 line, which was derived from autologous somatic cell nuclear transfer (SCNT), we compared the expression and methylation patterns of
Stefania Corvaglia et al.
Scientific reports, 4, 5366-5366 (2014-06-21)
Intrinsically Disordered Proteins (IDPs) are characterized by the lack of well-defined 3-D structure and show high conformational plasticity. For this reason, they are a strong challenge for the traditional characterization of structure, supramolecular assembly and biorecognition phenomena. We show here
One single method to produce native and Tat-fused recombinant human α-synuclein in Escherichia coli.
Laura Caldinelli et al.
BMC biotechnology, 13, 32-32 (2013-04-06)
Human α-synuclein is a small-sized, natively unfolded protein that in fibrillar form is the primary component of Lewy bodies, the pathological hallmark of Parkinson's disease. Experimental evidence suggests that α-synuclein aggregation is the key event that triggers neurotoxicity although additional
Yunden Jinsmaa et al.
The Journal of pharmacology and experimental therapeutics, 372(2), 157-165 (2019-11-21)
Lewy body diseases such as Parkinson's disease involve intraneuronal deposition of the protein α-synuclein (AS) and depletion of nigrostriatal dopamine (DA). Interactions of AS with DA oxidation products may link these neurohistopathologic and neurochemical abnormalities via two potential pathways: spontaneous
Lisa Fellner et al.
Glia, 61(3), 349-360 (2012-10-31)
Alpha-synucleinopathies (ASP) are neurodegenerative disorders, characterized by accumulation of misfolded α-synuclein, selective neuronal loss, and extensive gliosis. It is accepted that microgliosis and astrogliosis contribute to the disease progression in ASP. Toll-like receptors (TLRs) are expressed on cells of the
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