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Merck
CN
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文件

安全信息

SRP0426

Sigma-Aldrich

PDE1B active rat

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

别名:

PDE1B1, PDES1B, phosphodiesterase 1B, calmodulin-dependent

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

rat

重组

expressed in baculovirus infected Sf9 cells

检测方案

≥70% (SDS-PAGE)

形式

aqueous solution

分子量

89 kDa

包装

pkg of 10 μg

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

rat ... PDE1B(5153)

一般描述

Rat PDE1B (GenBank Accession No. NM_022710) full length with N-terminal HIS-GST-tag, MW= 89kDa, expressed in a Baculovirus infected Sf9 cell expression system.

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Andrew T Bender et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(2), 497-502 (2004-12-31)
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a major regulator of monocyte to macrophage differentiation. In both humans and mice, the main phenotype of decreased GM-CSF function is pulmonary proteinosis due to aberrant function of alveolar macrophages. Recently, this cytokine has been
Andrew T Bender et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(2), 460-465 (2006-01-13)
Monocyte-to-macrophage differentiation with the cytokine granulocyte-macrophage colony-stimulating factor induces expression of the cyclic nucleotide phosphodiesterase PDE1B2. However, what role PDE1B2 plays in macrophage biology has not been elucidated. We have addressed this question by inhibiting PDE1B2 induction by using RNA

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