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Merck
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PDE1B

phosphodiesterase 1B, calmodulin-dependent

别名:
PDE1B1, PDES1B
物种:
UniProtKB ID:
基因ID:
  • Human(5153) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(18574) phosphodiesterase 1B, Ca2+-calmodulin dependent
  • Rat(29691) phosphodiesterase 1B, calmodulin-dependent
  • domestic guinea pig(100527959) phosphodiesterase 1B, Ca2+-calmodulin dependent
  • naked mole-rat(101718122) phosphodiesterase 1B, calmodulin-dependent
  • sheep(101118773) phosphodiesterase 1B, calmodulin-dependent
  • Domestic Rabbit(100341084) phosphodiesterase 1B, calmodulin-dependent
  • Horse(100064711) phosphodiesterase 1B, calmodulin-dependent
  • cow(281970) phosphodiesterase 1B, calmodulin-dependent
  • dog(100856025) phosphodiesterase 1B, calmodulin-dependent
  • domestic cat(101094608) phosphodiesterase 1B, calmodulin-dependent

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-PDE1B, (C-terminal) antibody produced in mouse, clone 4F9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-PDE1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
物种
human
咯利普兰, solid, ≥98% (HPLC),
物种
human, mouse, rat
双嘧达莫, United States Pharmacopeia (USP) Reference Standard,
物种
human
双嘧达莫, European Pharmacopoeia (EP) Reference Standard,
物种
human
双嘧达莫杂质标准品, British Pharmacopoeia (BP) Reference Standard,
物种
human

Proteins

货号
说明
物种
PDE1B Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
物种
human
PDE1B active rat, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Pde1b,
物种
mouse
MISSION® esiRNA, targeting human PDE1B,
物种
human