所有图片(1)
别名:
2-(2-硝基-4-三氟甲基苯甲酰基)-1,3-环己二酮, 2-[2-硝基-4-（三氟甲基）苯甲酰基] 环己烷-1,3-二酮, NTBC, SC 0735, 尼替松
经验公式（希尔记法）:
C14H10F3NO5
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质量水平
检测方案
≥95% (HPLC)
形式
powder
颜色
white to brown
溶解性
DMSO: ≥5 mg/mL
储存温度
−20°C
SMILES字符串
[O-][N+](=O)c1cc(ccc1C(=O)C2C(=O)CCCC2=O)C(F)(F)F
InChI
1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,12H,1-3H2
InChI key
OUBCNLGXQFSTLU-UHFFFAOYSA-N
基因信息
human ... HPD(3242)
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应用
尼替西农已经被用于：
- 诱导肝损伤
- 治疗 肩突硬蜱 细胞，抑制羟苯丙酮酸双加氧酶
- 在补充水中的活性以阻止有毒代谢产物在人肝细胞移植小鼠中的蓄积，
- 以研究其对细菌性脓疱素产生的影响。
生化/生理作用
尼替西农是一种竞品抑制剂，可逆地抑制4-羟苯基丙酮酸氧化酶（双加氧酶）。尼替西农用于治疗1型遗传性酪氨酸血症，可阻止酪氨酸降解为有害物质。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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