SML0255
4-DAMP
≥98% (HPLC)
别名:
1,1-二甲基-4-二苯基乙酰氧基哌啶碘化物, 4-[(二苯基乙酰基)氧基] -1,1-二甲基碘化哌啶, 4-二苯乙酰氧基-N-甲基-哌啶甲碘化物, 4-二苯基乙酰氧基-N-甲基哌啶甲硫醇
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选择尺寸
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关于此项目
经验公式（希尔记法）:
C21H26INO2
化学文摘社编号:
分子量:
451.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: ≥15 mg/mL
storage temp.
room temp
SMILES string
[I-].C[N+]1(C)CCC(CC1)OC(=O)C(c2ccccc2)c3ccccc3
InChI
1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1
InChI key
WWJHRSCUAQPFQO-UHFFFAOYSA-M
Biochem/physiol Actions
4-DAMP 是 M3 型选择性胆碱能受体拮抗剂。
4-DAMP 是毒蕈碱受体拮抗剂；M3 型选择性胆碱能受体拮抗剂。
Features and Benefits
该化合物在受体分类和信号转导手册的 乙酰胆碱受体（毒蕈碱） 页面上有详细描述。想要浏览手册的其他页面， 请单击此处。
这种化合物是神经科学研究的特色产品。点击此处发现更多特色神经科学产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.
DISCOVER Bioactive Small Molecules for Neuroscience
Qiang Liu et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 44(3), 907-919 (2017-11-28)
Overactive bladder associated with bladder outlet obstruction (BOO) is a highly prevalent condition, which is usually treated with antimuscarinics. However, the potential effects of antimuscarinics on the structure and function of bladder have not been investigated thus far. Sprague-Dawley(R) rats
Hyun Jung Kim et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(5), 1790-1802 (2017-10-20)
Magnolia officinalis Rehder and EH Wilson (M. officinalis) are traditional Chinese medicines widely used for gastrointestinal (GI) tract motility disorder in Asian countries. We investigated the effects of an ethanol extract of M. officinalis (MOE) on the pacemaker potentials of
Shohei Yamaguchi et al.
Food chemistry, 276, 376-382 (2018-11-10)
Our previous results (Nakamura et al., 2013, 2016) indicated that acetylcholine (ACh) in orally administered foods exerts antihypertensive effects. Eggplants (Solanum melongena) contain abundant ACh (Horiuchi et al., 2003), and their food functionality was discovered, using spontaneously hypertensive rats, by
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML0255-50MG | 04061832075334 |
| SML0255-10MG | 04061832075327 |