质量水平
检测方案
≥98% (HPLC)
形式
powder
储存条件
desiccated
颜色
white to tan
溶解性
H2O: ≥15 mg/mL at ~60 °C
储存温度
−20°C
SMILES字符串
Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2
InChI
1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1
InChI key
LWWSARSTZGNKGV-FVGYRXGTSA-N
应用
Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.
生化/生理作用
Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.
Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.
Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.
特点和优势
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Aceclidine effects on outflow facility after ciliary muscle disinsertion
Hubbard WC, et al.
Ophthalmologica, 210(5), 303-307 (1996)
Double-blind cross-over comparison of aceclidine and pilocarpine in open-angle glaucoma.
J H Romano
The British journal of ophthalmology, 54(8), 510-521 (1970-08-01)
商品
Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.
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