推荐产品
产品名称
L -茶氨酸, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
off-white
mp
217-218 °C
应用
cell analysis
储存温度
2-8°C
SMILES字符串
CCNC(=O)CC[C@H](N)C(O)=O
InChI
1S/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
InChI key
DATAGRPVKZEWHA-YFKPBYRVSA-N
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一般描述
L-茶氨酸是谷氨酰胺的类似物，也是绿茶的成分之一。
应用
- Safety and Efficacy of AlphaWave L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.：该临床试验表明补充L-茶氨酸可有效减轻压力和提升认知功能，且无副作用。(Moulin et al., 2024)。
- Inhibitory Role of L-theanine, a Structural Analogue of Glutamate, Against GluR5 Kainate Receptor and its Prospective Utility Against Excitotoxicity.：本文探讨L-茶氨酸可通过抑制特定的谷氨酸受体带来抗神经毒性保护作用(Deb and Borah, 2024)(Deb and Borah, 2024)。
- L-theanine abates oxidative stress and mitochondrial dysfunction in myocardial ischemia-reperfusion injury by positively regulating the antioxidant response.：本文表明L-茶氨酸的心脏保护作用，它可在心脏损伤时减轻氧化应激和提升线粒体功能。(García-Niño et al., 2024)。
生化/生理作用
L-茶氨酸可调节几种抗肿瘤药物的活性，据报道，它可刺激人类胚胎干细胞的自我更新。L-茶氨酸与 AMPA、红藻氨酸、NMDA 和 I 型 mGlu 受体结合。
茶氨酸能够与大鼠皮层神经元的 AMPA、钾盐镁矾和 NMDA 甘氨酸受体结合但亲和力低于谷氨酸。已对其作为谷氨酸盐转运抑制剂进行了研究，防止荷 M5076 卵巢肉瘤小鼠细胞摄取谷氨酸盐，并增加多柔比星对 M5076 小鼠肿瘤生长的影响。
其他说明
茶氨酸是一种谷氨酰胺的氨基酸类似物，存在于绿茶中。
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Chen Qi et al.
Journal of AOAC International, 103(2), 428-432 (2019-09-20)
In order to make up for the efficacy of sensory assessment of green tea quality and taste, main flavor substances should be quantitatively characterized based on efficient extraction and frontier determination scheme. A new, relatively simple sample preparation and detection
G V V Liyanaarachchi et al.
Food chemistry, 240, 196-203 (2017-09-28)
The study presents the validation results of the method carried out for analysis of free amino acids (FAAs) in rice using l-theanine as the internal standard (IS) with o-phthalaldehyde (OPA) reagent using high-performance liquid chromatography-fluorescence detection. The detection and quantification
Li Zeng et al.
Experimental gerontology, 131, 110823-110823 (2020-01-04)
Redox and inflammation imbalances are associated with increased levels of advanced glycation end products (AGEs), leading to the degeneration of body function. l-Theanine, derived from tea, reportedly inhibits AGE formation in vitro. We investigated the effects on AGE content, oxidative
Guoqi Zhu et al.
Neuropharmacology, 138, 331-340 (2018-06-27)
Synaptic refinement improves synaptic efficiency, which provides a possibility to improve memory in Alzheimer's disease (AD). In the current study, we aimed to investigate the role of L-theanine, a natural constituent in green tea, in hippocampal synaptic transmission and to
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