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Merck
CN

SMB00395

Sigma-Aldrich

L -茶氨酸

≥98% (HPLC)

别名:

Nγ-乙基-L-谷氨酰胺, L-谷氨酸γ-(乙酰胺), Suntheanine茶氨酸

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About This Item

经验公式(希尔记法):
C7H14N2O3
CAS号:
分子量:
174.20
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.25

产品名称

L -茶氨酸, ≥98% (HPLC)

质量水平

方案

≥98% (HPLC)

表单

powder

颜色

off-white

mp

217-218 °C

应用

cell analysis

储存温度

2-8°C

SMILES字符串

CCNC(=O)CC[C@H](N)C(O)=O

InChI

1S/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1

InChI key

DATAGRPVKZEWHA-YFKPBYRVSA-N

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一般描述

L-茶氨酸是谷氨酰胺的类似物,也是绿茶的成分之一。

应用


  • Safety and Efficacy of AlphaWave L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.: This clinical trial demonstrates that L-theanine supplementation effectively reduces stress and improves cognitive function without adverse effects (Moulin et al., 2024). (Moulin et al., 2024).

  • Inhibitory Role of L-theanine, a Structural Analogue of Glutamate, Against GluR5 Kainate Receptor and its Prospective Utility Against Excitotoxicity.: The study examines L-theanine′s potential in protecting against neurotoxicity by inhibiting specific glutamate receptors (Deb and Borah, 2024). (Deb and Borah, 2024).

  • L-theanine abates oxidative stress and mitochondrial dysfunction in myocardial ischemia-reperfusion injury by positively regulating the antioxidant response.: This research demonstrates the cardioprotective effects of L-theanine, highlighting its role in reducing oxidative stress and improving mitochondrial function during heart injuries (García-Niño et al., 2024). (García-Niño et al., 2024).

生化/生理作用

L-茶氨酸可调节几种抗肿瘤药物的活性,据报道,它可刺激人类胚胎干细胞的自我更新。L-茶氨酸与 AMPA、红藻氨酸、NMDA 和 I 型 mGlu 受体结合。
茶氨酸能够与大鼠皮层神经元的 AMPA、钾盐镁矾和 NMDA 甘氨酸受体结合但亲和力低于谷氨酸。已对其作为谷氨酸盐转运抑制剂进行了研究,防止荷 M5076 卵巢肉瘤小鼠细胞摄取谷氨酸盐,并增加多柔比星对 M5076 小鼠肿瘤生长的影响。

其他说明

茶氨酸是一种谷氨酰胺的氨基酸类似物,存在于绿茶中。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Chen Qi et al.
Journal of AOAC International, 103(2), 428-432 (2019-09-20)
In order to make up for the efficacy of sensory assessment of green tea quality and taste, main flavor substances should be quantitatively characterized based on efficient extraction and frontier determination scheme. A new, relatively simple sample preparation and detection
Guoqi Zhu et al.
Neuropharmacology, 138, 331-340 (2018-06-27)
Synaptic refinement improves synaptic efficiency, which provides a possibility to improve memory in Alzheimer's disease (AD). In the current study, we aimed to investigate the role of L-theanine, a natural constituent in green tea, in hippocampal synaptic transmission and to
G V V Liyanaarachchi et al.
Food chemistry, 240, 196-203 (2017-09-28)
The study presents the validation results of the method carried out for analysis of free amino acids (FAAs) in rice using l-theanine as the internal standard (IS) with o-phthalaldehyde (OPA) reagent using high-performance liquid chromatography-fluorescence detection. The detection and quantification
Li Zeng et al.
Experimental gerontology, 131, 110823-110823 (2020-01-04)
Redox and inflammation imbalances are associated with increased levels of advanced glycation end products (AGEs), leading to the degeneration of body function. l-Theanine, derived from tea, reportedly inhibits AGE formation in vitro. We investigated the effects on AGE content, oxidative

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