SAB6012223
Anti-phospho-beta Catenin (Thr41/Ser45) Antibody, clone 23GB3875, Rabbit Monoclonal
clone 23GB3875, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
ARMADILLO, CTNNB, EVR7, MRD19, NEDSDV
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UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
23GB3875, recombinant monoclonal
Application:
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Species reactivity:
human, rat
Citations:
Technique(s):
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
Uniprot accession no.:
产品名称
Anti-phospho-beta Catenin (Thr41/Ser45) Antibody, clone 23GB3875, Rabbit Monoclonal, clone 23GB3875, recombinant rabbit monoclonal, expressed in HEK293 cells
biological source
rabbit (Monoclonal)
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB3875, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
85 kDa
species reactivity
human, rat
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
Quality Level
Gene Information
human ... CTNNB1(1499)
sustainability
Greener Alternative Product
concentration
1.5 mg/ml
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
NCBI accession no.
UniProt accession no.
greener alternative category
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 38-52 of human Phospho-beta Catenin (T41 + S45) [NP_001895.1].
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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