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Merck
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CTNNB1

catenin (cadherin-associated protein), beta 1, 88kDa

别名:
CTNNB, MRD19, armadillo
物种:
UniProtKB ID:
基因ID:
  • Human(1499) Summary: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(12387) catenin (cadherin associated protein), beta 1
  • Rat(84353) catenin (cadherin associated protein), beta 1
  • Zebrafish(30265) catenin (cadherin-associated protein), beta 1
  • Horse(100055241) catenin (cadherin-associated protein), beta 1, 88kDa
  • chicken(395964) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic guinea pig(100732604) catenin (cadherin-associated protein), beta 1, 88kDa
  • cow(539003) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic cat(101097342) catenin (cadherin-associated protein), beta 1, 88kDa
  • sheep(100294600) catenin (cadherin-associated protein), beta 1, 88kDa
  • dog(477032) catenin (cadherin-associated protein), beta 1, 88kDa
  • Domestic Rabbit(100125985) catenin (cadherin-associated protein), beta 1, 88kDa
  • naked mole-rat(101720578) catenin (cadherin-associated protein), beta 1, 88kDa

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Antibodies

货号
说明
物种反应性
应用
单克隆抗-β-连环蛋白 小鼠抗, clone 15B8, ascites fluid,
物种反应性
bovine, canine, chicken, human
应用
immunocytochemistry
immunofluorescence

immunohistochemistry

microarray

western blot
单克隆抗-β-连环蛋白, clone 15B8, purified from hybridoma cell culture,
物种反应性
bovine, canine, chicken, human
应用
immunofluorescence
单克隆抗-β-连环蛋白 小鼠抗, clone 6F9, ascites fluid,
物种反应性
bovine, canine, chicken, human
应用
immunofluorescence
microarray

western blot
抗-CTNNB1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-CTNNB1 (Ab-654) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot

Cell Lines

货号
说明
物种
A549 Cells GFP-CTNNB1 RFP-LMNB1, ,
物种
human

Proteins

货号
说明
物种
Catenin β, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CTNNB1,
物种
human
MISSION® esiRNA, targeting mouse Ctnnb1,
物种
mouse