生物来源
rabbit
质量水平
物料
colorless
克隆
5T6S8, monoclonal
表单
liquid
分子量
49 kDa
种属反应性
rat, rat, human
浓度
1.00 mg/mL
技术
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
颜色
colorless
同位素/亚型
IgG
免疫原序列
STAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PDK1(5163)
一般描述
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 337-436 of human PDK1/PDHK1 (NP_002601.1).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
应用
WB, IHC
警示用语:
Warning
危险声明
危险分类
Aquatic Chronic 2 - Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 3
法规信息
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