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重组
expressed in HEK 293 cells
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
RM296, monoclonal
recombinant monoclonal
形式
buffered aqueous glycerol solution
种属反应性
human
技术
immunohistochemistry: 1:100-1:200
western blot: 1:100-1:200
同位素/亚型
IgG
NCBI登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
phosphorylation (pSer845)
基因信息
human ... GRIA1(2890)
一般描述
GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is located on human chromosome 5q33.2. It is expressed mainly in brain areas.
特异性
This antibody reacts to human Glutamate Receptor 1, AMPA Receptor (GluR1) only when phosphorylated at Ser845. There is no cross-reactivity to GluR1 that is not phosphorylated at Ser845. This antibody may also react to mouse or rat Phospho-AMPA Receptor (GluR1) (Ser845) as predicted by immunogen homology.
免疫原
A phospho-peptide corresponding to human Phospho-Glutamate Receptor 1 (GluR1) (Ser845).
生化/生理作用
GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It is associated with migraine.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
含少量动物源组分生物产品
常规特殊物品
Selective disruption of stimulus-reward learning in glutamate receptor gria1 knock-out mice
Mead AN and Stephens DN
The Journal of Neuroscience, 23(3), 1041-1048 (2003)
Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility
Formicola D, et al.
BMC Medical Genetics, 11(1), 103-103 (2010)
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