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一般描述
Placental alkaline phosphatase (PLAP) or ALPP is a phosphomonoesterase. It is expressed in the placenta and endometrium. The PLAP gene is localized on human chromosome 2q37.1.
免疫原
Recombinant protein encoding human placental alkaline phosphatase.
生化/生理作用
Placental alkaline phosphatase (PLAP) or ALPP is a hydrolase, which is involved in the hydrolysis of phosphomonoesters. It has been shown to be a biomarker for ovarian cancer. The protein is expressed in carcinomas such as ovarian adenocarcinoma, dysgerminoma, serous cystadenocarcinoma and undifferentiated carcinoma.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
Genome wide expression profile in human HTR-8/Svneo trophoblastic cells in response to overexpression of placental alkaline phosphatase gene.
Bellazi L
Placenta (2011)
Cloverleaf skull anomaly and de novo
trisomy 4p
trisomy 4p
Journal of medical Genetics (1999)
A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer.
Ravenni N
MAbs (2014)
Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.
Stec B
Acta Crystallographica Section F, Structural Biology and Crystallization Communications (2010)
Human placental alkaline phosphatase-mediated hydrolysis correlates tightly with the electrostatic contribution from tail group.
Yang Y
Chemical Biology & Drug Design (2011)
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