推荐产品
生物来源
rabbit
重组
expressed in proprietary host
偶联物
unconjugated
抗体形式
tissue culture supernatant
抗体产品类型
primary antibodies
克隆
SP1, monoclonal
种属反应性
human (tested)
种属反应性（根据同源性预测）
pig
技术
immunoblotting: 1:25
immunohistochemistry: 1:200
同位素/亚型
IgG
UniProt登记号
运输
wet ice
储存温度
2-8°C
基因信息
human ... ESR1(2099)
一般描述
The estrogen receptor 1 (ESR1) gene is mapped to human chromosome 6q25.1.
This antibody recognizes a protein of 67kDa, which is identified as estrogen receptor (ER). This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland.
免疫原
Synthetic peptide derived from C-terminus of human estrogen receptor alpha.
生化/生理作用
Estrogen receptor 1 (ESR1) is known to be a part of bone tissue phenotypes. The ESR1 gene encodes a steroid hormone receptor, which acts as a transcription factor. Estrogen activated ESR1 induces cell proliferation. Estrogen receptor participates in the pathogenesis of breast cancer.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Estrogen receptor α wields treatment-specific enhancers between morphologically similar endometrial tumors.
Droog M, et al.
Proceedings of the National Academy of Sciences of the USA, 114(8), E1316-E1325 (2017)
Genome-wide association study identifies a novel breast cancer susceptibility locus at 6q25.1.
Zheng w, et al.
Nature Genetics, 41(3), 324-324 (2009)
Estrogen Receptor Mediates the Radiosensitivity of Triple-Negative Breast Cancer Cells.
Chen X, et al.
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 23, 2674-2674 (2017)
Association study of estrogen receptor alpha gene polymorphisms with bone mass assessed by quantitative ultrasound in young adults.
Correa-Rodriguez M, et al.
Rheumatology International, 37(8), 1281-1286 (2017)
Paul Stockhammer et al.
Pathology oncology research : POR, 27, 636088-636088 (2021-07-15)
Objective: Uterine carcinosarcoma (UCS) is a rare but highly aggressive malignancy with biphasic growth pattern. This morphology can be attributed to epithelial-mesenchymal transition (EMT) that often associates with tumor invasion and metastasis. Accordingly, we analyzed a novel patient-derived preclinical model
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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