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安全信息

SAB5200222

Sigma-Aldrich

Monoclonal Anti-Kcc2 antibody produced in mouse

clone S1-12, purified immunoglobulin

别名:

Anti-Electroneutral potassium chloride cotransporter 2, Anti-Potassium Chloride Cotransporter, Anti-SLC12A5, Anti-hKCC2

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

S1-12, monoclonal

形式

buffered aqueous solution

分子量

antigen predicted mol wt 140 kDa

种属反应性

mouse, human, rat

浓度

1 mg/mL

技术

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG2a

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

相关类别

特异性

Detects ~140kDa.

免疫原

Fusion protein amino acids 932-1043 corresponding to rat KCC2

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

PBS pH7.4, 50% glycerol, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Lulan Chen et al.
Scientific reports, 7(1), 156-156 (2017-03-11)
GABAA receptor-mediated inhibition depends on the maintenance of low level intracellular [Cl-] concentration, which in adult depends on neuron specific K+-Cl- cotransporter-2 (KCC2). Previous studies have shown that KCC2 was downregulated in both epileptic patients and various epileptic animal models.

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