推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous glycerol solution
分子量
antigen predicted mol wt 28.8 kDa
种属反应性
human, mouse, rat
浓度
1 mg/mL
技术
indirect immunofluorescence: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
rat ... Aqp2(25386)
一般描述
The gene ID of the protein aquaporin-2 (AQP2) is 25386.
特异性
Detects ~28.8 kDa. May detect larger glycosylated bands ~35-50 kDa.
免疫原
C-terminal peptide
生化/生理作用
Aquaporin 2 (AQP2) takes part in maintaining the water balance in cells. A high concentration of the protein has been observed in rats during hypothyroidism.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Peter Kösters et al.
Cells, 13(10) (2024-05-24)
Uncovering the function of understudied G protein-coupled receptors (GPCRs) provides a wealth of untapped therapeutic potential. The poorly understood adhesion GPCR Gpr126 (Adgrg6) is widely expressed in developing kidneys. In adulthood, Gpr126 expression is enriched in parietal epithelial cells (PECs)
Salvador Cazorla-Vázquez et al.
Cells, 12(15) (2023-08-11)
Adhesion G protein-coupled receptors (aGPCRs) comprise the second-largest class of GPCRs, the most common target for approved pharmacological therapies. aGPCRs play an important role in development and disease and have recently been associated with the kidney. Several aGPCRs are expressed
Lorena I Sarati et al.
Metabolism: clinical and experimental, 62(9), 1287-1295 (2013-05-28)
Hypothyroid state and aging are associated with impairment in water reabsorption and changes in aquaporin water channel type 2 (AQP2). Nitric oxide (NO) is involved in AQP2 trafficking to the apical plasma membrane in medullary collecting duct cells. The purpose
William J Monis et al.
The Journal of cell biology, 216(7), 2131-2150 (2017-06-04)
Primary cilia perceive the extracellular environment through receptors localized in the ciliary membrane, but mechanisms directing specific proteins to this domain are poorly understood. To address this question, we knocked down proteins potentially important for ciliary membrane targeting and determined
Naohiro Nomura et al.
American journal of physiology. Cell physiology, 307(7), C597-C605 (2014-06-20)
A reduction or loss of plasma membrane aquaporin 2 (AQP2) in kidney principal cells due to defective vasopressin (VP) signaling through the VP receptor causes excessive urine production, i.e., diabetes insipidus. The amount of AQP2 on the plasma membrane is
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