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主要文件

安全信息

SAB5200073

Sigma-Aldrich

Monoclonal Anti-KCNIP3 antibody produced in mouse

clone S66-38, 1 mg/mL, purified immunoglobulin

别名:

Anti-Csen, Anti-Dream, Anti-KChlP3 K+ channel, S66-38, Anti-Kcnip3, Anti-rKChIP3

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

S66-38, monoclonal

表单

buffered aqueous glycerol solution

分子量

antigen predicted mol wt 34 kDa

种属反应性

mouse, human, rat

浓度

1 mg/mL

技术

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG2a

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

相关类别

一般描述

Potassium voltage-gated channel interacting protein 3 (KCNIP3) is part of the neuronal calcium sensor protein family. The gene ID of the protein is 65199.

特异性

Detects ~34 kDa. No cross reactivity against KCIPs 1,2 or 4

免疫原

Fusion protein amino acids 1-256 (Full lenght) of rat Calsenillin/DREAM/KChIP3

生化/生理作用

Potassium voltage-gated channel interacting protein 3 (KCNIP3) is involved in the downregulation of other genes. It has been shown that the protein is upregulated when there is a high concentration of glucose in vitro.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

Rosfaiizah Siran et al.
Journal of physiology and biochemistry, 70(4), 877-889 (2014-09-15)
REM sleep is a crucial component of sleep. Animal studies indicate that rapid eye movement (REM) sleep deprivation elicits changes in gene expression. Down regulatory antagonist modulator (DREAM) is a protein which downregulates other gene transcriptions by binding to the
Erika Chavira-Suárez et al.
Biochemical and biophysical research communications, 418(2), 420-425 (2012-01-27)
Hyperglycemia alters the tight control of intracellular calcium dynamics in retinal cells and may lead to the development of diabetic retinopathy. The potassium channel interacting protein 3 (KChIP3) also known as DREAM (Downstream Regulatory Element Antagonist Modulator) or calsenilin (KChIP3/DREAM/calsenilin)

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