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生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
BB7.2, monoclonal
表单
buffered aqueous solution
种属反应性
human
浓度
1 mg/mL
技术
flow cytometry: suitable
immunoprecipitation (IP): suitable
同位素/亚型
IgG2b
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
human ... HLA-A(3105)
一般描述
Human leukocyte antigen A α-chain (HLA-A2) is encoded by the gene mapped to human chromosome 6p22.1. HLA-A belongs to the class I molecules of HLa family. The protein structure consists of two polypeptide chains, heavy chain and the non-covalently attached light chain.
The antibody BB7.2 recognizes an epitope at the C-terminus of alpha-2 helix and a turn on one of the underlying beta strands within the human HLA-A2 histocompatibility antigen.
The previously assigned protein identifier P01891 has been merged into P04439. Full details can be found on the UniProt database.
The previously assigned protein identifier P01891 has been merged into P04439. Full details can be found on the UniProt database.
免疫原
HLA-A2 solubilized by papain
应用
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5-10 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
生化/生理作用
Human leukocyte antigen A α-chain (HLA-A2) plays a major role in peptide antigen presentation. The encoded protein interacts with cytotoxic T cells (CTL) and facilitates the identification of peptide derived from the influenza matrix protein.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in azide free phosphate buffered saline, pH 7.4; 0.2 um filter sterilized.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2
Gotch F
Nature, 326, 881-882 (1987)
Structure of the human class I histocompatibility antigen, HLA-A2.
Bjorkman PJ
Nature, 329, 506-512 (1987)
Modern vitiligo genetics sheds new light on an ancient disease
Spritz RA
The Journal of Dermatology, 40, 310-318 (2013)
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