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安全信息

SAB4700183

Sigma-Aldrich

Monoclonal Anti-CD44-PE antibody produced in mouse

clone MEM-85, purified immunoglobulin, buffered aqueous solution

别名:

Anti-Pgp-1

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.44

生物来源

mouse

质量水平

偶联物

phycoerythrin (R-PE) conjugate

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

MEM-85, monoclonal

形式

buffered aqueous solution

种属反应性

human

技术

flow cytometry: suitable

同位素/亚型

IgG2b

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

基因信息

human ... CD44(960)

一般描述

The antibody MEM-85 reacts with both cell surface-expressed and soluble form of CD44 antigen (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes.

免疫原

Leukocytes of a patient suffering from LGL Type Leukaemia.

应用

The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Maksudbek Yusupov et al.
Redox biology, 43, 101968-101968 (2021-04-26)
Multiple cancer therapies nowadays rely on oxidative stress to damage cancer cells. Here we investigated the biological and molecular effect of oxidative stress on the interaction between CD44 and hyaluronan (HA), as interrupting their binding can hinder cancer progression. Our

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