推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 41 kDa
种属反应性
mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:20000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... 5NT1A(84618)
一般描述
Anti-NT5C1A Antibody detects endogenous levels of total NT5C1A protein. The NT5C1A (5′-nucleotidase, cytosolic IA) gene is mapped to human chromosome 1p34. The protein encoded is ubiquitously expressed and is localized to the cytoplasm.
免疫原
The antiserum was produced against synthesized peptide derived from human NT5C1A.
Immunogen Range: 151-200
Immunogen Range: 151-200
生化/生理作用
NT5C1A (5′-nucleotidase, cytosolic IA) forms a tetramer with AMP (adenosine monophosphate) and serves as a primary substrate in adenosine pathway to control the level of metabolite produced. NT5C1A catalyzes the dephosphorylation of AMP to adenosine.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Pharmacogenetic characterization of naturally occurring germline NT5C1A variants to chemotherapeutic nucleoside analogs.
Saliba J, et al.
Pharmacogenetics and Genomics, 26(6), 271-271 (2016)
Suppression of 5'nucleotidase enzymes promotes AMPK phosphorylation and metabolism in human and mouse skeletal muscle.
Kulkarni S S, et al.
The Journal of Biological Chemistry (2011)
Expression of cytosolic 5? nucleotidase does not correlate with expression of oxidative metabolism marker: myoglobine in human skeletal muscles.
Lechward K and Tkacz-Stachowska K
Acta biochimica et biophysica Sinica, 41(4), 280-284 (2009)
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