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生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 93 kDa
种属反应性
human
浓度
~1 mg/mL
技术
ELISA: 1:10000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... TAS1R3(83756)
一般描述
Taste receptor family 1 member 3 (TAS1R3) gene encodes for sweet taste receptor T1R3 protein. T1R3 protein belongs to the family of 3 subtypes of G-protein coupled receptors (GPCRs). This protein is localized in the taste bud cells of the oral cavity. The TAS1R3 gene is mapped on the human chromosome at 1p36.33.
免疫原
The antiserum was produced against synthesized peptide derived from human TAS1R3.
Immunogen Range: 326-375
Immunogen Range: 326-375
应用
Anti-TAS1R3 antibody produced in rabbit has been used in immunohistochemistry and immunocytochemistry.
生化/生理作用
Sweet taste receptor T1R3 protein plays a role in membrane glucose sensing and regulates glucose homeostasis in endocrine cells..
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.
Max, et al.
Nature Genetics, 28, 58-63 (2019)
Mariam Raliou et al.
Neuroscience letters, 451(3), 217-221 (2009-01-17)
Monosodium glutamate as well as metabotropic and ionotropic glutamate receptor agonists have been reported to be perceived as umami by humans. In spite of the fact that Tas1R1-Tas1R3 has been shown to mediate most of the glutamate taste sensation in
Marco Tizzano et al.
Chemical senses, 40(9), 655-660 (2015-09-25)
The morphology of the vallate papillae from postmortem human samples was investigated with immunohistochemistry. Microscopically, taste buds were present along the inner wall of the papilla, and in some cases in the outer wall as well. The typical taste cell
Vladimir O Murovets et al.
PloS one, 10(6), e0130997-e0130997 (2015-06-25)
The G-protein-coupled sweet taste receptor dimer T1R2/T1R3 is expressed in taste bud cells in the oral cavity. In recent years, its involvement in membrane glucose sensing was discovered in endocrine cells regulating glucose homeostasis. We investigated importance of extraorally expressed
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