生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 88 kDa
种属反应性
mouse, rat, human
浓度
~1 mg/mL
技术
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ZNF148(7707)
一般描述
Anti-ZNF148 Antibody detects endogenous levels of total ZNF148 protein.
The ZNF148 (zinc finger protein 148) gene is mapped to human chromosome 3q21.2. The encoded protein contains four C2H2 zinc finger motifs.
免疫原
The antiserum was produced against synthesized peptide derived from human ZNF148.
Immunogen Range: 61-110
Immunogen Range: 61-110
生化/生理作用
Znf148 (zinc finger protein 148) is known to regulate cell growth and apoptosis. ZNF148 is involved in tumor growth, invasion and metastasis. Znf148 possesses tumor suppressor activity. Upregulation of the ZNF148 gene is observed in colorectal cancer and Znf148 brings about apoptosis, induced by p53-dependent or in an independent manner in cancer cells.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Truncating de novo mutations in the Kruppel-type zinc-finger gene ZNF148 in patients with corpus callosum defects, developmental delay, short stature, and dysmorphisms
Stevens SJ, et al.
Genome Medicine, 8(1), 131-131 (2016)
Expression of ZNF148 in different developing stages of colorectal cancer and its prognostic value: a large Chinese study based on tissue microarray.
Gao XH, et al.
Cancer, 119(12), 2212-2222 (2013)
Interaction between ZBP-89 and p53 mutants and its contribution to effects of HDACi on hepatocellular carcinoma
Zhang CZ, et al.
Cell Cycle, 11(2), 322-334 (2012)
High-expression of ZBP-89 correlates with distal metastasis and poor prognosis of patients in clear cell renal cell carcinoma.
Cai MY, et al.
Biochemical and Biophysical Research Communications, 426(4), 636-642 (2012)
Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease
Bomprezzi R, et al.
Human Molecular Genetics, 12(17), 2191-2199 (2003)
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