生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 23 kDa
种属反应性
human, rat, mouse
浓度
~1 mg/mL
技术
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... TP53INP2(58476)
mouse ... T53I2(68728)
一般描述
Anti-TP53INP2 Antibody detects endogenous levels of total TP53INP2 protein.
TP53INP2/DOR (tumor protein p53 inducible nuclear protein 2) is located in the nucleolus. It is ubiquitously present in the tissues, with a high metabolism level. TP53INP2 is located on human chromosome 20q11.22.
TP53INP2/DOR (tumor protein p53 inducible nuclear protein 2) is located in the nucleolus. It is ubiquitously present in the tissues, with a high metabolism level. TP53INP2 is located on human chromosome 20q11.22.
免疫原
The antiserum was produced against synthesized peptide derived from human TP53INP2.
Immunogen Range: 1-50
Immunogen Range: 1-50
生化/生理作用
TP53INP2/DOR (tumor protein p53 inducible nuclear protein 2) acts as a promoter of autophagy and is involved in cell catabolism. It is essential for rDNA transcription. TP53INP2 is required for protein synthesis and cell proliferation. It also acts as a coactivator of the thyroid hormone receptor and regulates the activities of thyroid hormone.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
TP53INP2/DOR, a mediator of cell autophagy, promotes rDNA transcription via facilitating the assembly of the POLR1/RNA polymerase I preinitiation complex at rDNA promoters.
Xu Y, et al.
Autophagy, 12(7), 1118-1128 (2016)
Takaya Ishihara et al.
Cancer science, 99(10), 1940-1949 (2008-11-20)
Anaplastic thyroid carcinoma (ATC) is one of the most virulent of all human malignancies, with a mean survival time among patients of less than 1 year after diagnosis. To date, however, cytogenetic information on this disease has been very limited.
Hamish Crerar et al.
Neuron, 102(3), 553-563 (2019-03-12)
Neurons are extraordinarily large and highly polarized cells that require rapid and efficient communication between cell bodies and axons over long distances. In peripheral neurons, transcripts are transported along axons to growth cones, where they are rapidly translated in response
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