产品名称
抗突触素 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 33 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SYP(6855)
Application
兔抗突触素抗体可用于:
- 免疫细胞化学
- 蛋白质印迹法
- 免疫组化
抗突触素抗体适合用于免疫组化和蛋白质印迹。
Biochem/physiol Actions
突触素(synaptophysin,SYP)调节神经递质释放和突触可塑性。它维持突触囊泡的生物发生和再循环。SYP 可作为神经内分泌肿瘤的标志物。它可作为神经内分泌前列腺癌(NEPC)的强效标志物。该基因的突变与X染色体连锁智力障碍(X-linked intellectual disability)有关。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完全放心地试用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多。
General description
突触素是一种整合膜糖蛋白,位于神经细胞的突触前囊泡中。该蛋白可能调节胞外分泌和突触囊泡的形成。突触素由SYP基因编码,SYP的遗传变异可导致智力低下。抗突触素抗体可特异性检测内源性总突触素蛋白水平。
突触素(SYP)是突触囊泡的整合膜蛋白。在神经形成过程中,它在皮层突触末梢中表达。该基因位于人染色体Xp11.23上。
Immunogen
产生抗人突触素合成肽的抗血清。
免疫原范围:101-150
免疫原范围:101-150
Physical form
兔 IgG 溶于磷酸盐缓冲盐水(不含 Mg2+ 和 Ca2+),pH7.4,150mM NaCl,0.02% 叠氮化钠和 50% 甘油中。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Single cell transcriptome analysis of mouse carotid body glomus cells
Zhou T, et al.
The Journal of Physiology, 594(15), 4225-4251 (2016)
Synaptophysin expression on circulating tumor cells in patients with castration resistant prostate cancer undergoing treatment with abiraterone acetate or enzalutamide
Pal SK, et al.
Urologic Oncology, 36(4), 162-e1-162-e1 (2018)
3K3A-activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice.
Yaoming Wang et al.
Nature medicine, 22(9), 1050-1055 (2016-08-23)
Activated protein C (APC) is a blood protease with anticoagulant activity and cell-signaling activities mediated by the activation of protease-activated receptor 1 (F2R, also known as PAR1) and F2RL1 (also known as PAR3) via noncanonical cleavage. Recombinant variants of APC
X-linked intellectual disability-associated mutations in synaptophysin disrupt synaptobrevin II retrieval
Gordon SL and Cousin MA
The Journal of Neuroscience, 33(34), 13695-13700 (2013)
SAP97 Binding Partner CRIPT Promotes Dendrite Growth In Vitro and In Vivo
Zhang L, et al.
eNeuro, ENEURO-EN0175 (2017)
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