推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 92 kDa
种属反应性
rat, mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:40000
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SRPK1(6732)
一般描述
Anti-SRPK1 Antibody detects endogenous levels of total SRPK1 protein.
Serine-arginine protein kinase 1 (SRPK1) belongs to the SR kinase family. In mammals, SRPK1 is expressed in the central nervous system in a region- and neuron-specific manner. This gene is mapped to human chromosome 6p21.2-p21.3. SRPK1 is also expressed in several normal tissues like testis and pancreas.
Serine-arginine protein kinase 1 (SRPK1) belongs to the SR kinase family. In mammals, SRPK1 is expressed in the central nervous system in a region- and neuron-specific manner. This gene is mapped to human chromosome 6p21.2-p21.3. SRPK1 is also expressed in several normal tissues like testis and pancreas.
免疫原
The antiserum was produced against synthesized peptide derived from human SRPK1.
Immunogen Range: 521-570
Immunogen Range: 521-570
生化/生理作用
Serine-arginine protein kinase 1 (SRPK1) modulates angiogenesis. Suppressing SRPK1 prevents the development and migration in renal carcinoma cells. In normoxic condition, SRPK1 can increase the migration and invasion of glioma cells.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
SRPK1 dissimilarly impacts on the growth, metastasis, chemosensitivity and angiogenesis of glioma in normoxic and hypoxic conditions.
Wu Q, et al.
Journal of Cancer, 4(9), 727?735-727?735 (2013)
Knockdown of Serine?Arginine Protein Kinase 1 Inhibits the Growth and Migration in Renal Cell Carcinoma Cells.
Han X, et al.
Oncology Research, 25(3), 389-395 (2017)
Expression of SRPK1 in gliomas and its role in glioma cell lines viability.
Sigala I, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 37(7), 8699-8707 (2016)
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