生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 28 kDa
种属反应性
rat, mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... RPS6(6194)
一般描述
Anti-S6 Ribosomal protein antibody detects endogenous levels of total S6 Ribosomal protein protein.
The RPS6 (ribosomal protein S6) gene is mapped to human chromosome 9p22.1.
免疫原
The antiserum was produced against synthesized peptide derived from human S6 Ribosomal Protein.
Immunogen Range: 191-240
Immunogen Range: 191-240
生化/生理作用
The RPS6 (ribosomal protein S6) protein is involved in the 40S subunit assembling. RpS6 might be involved in the regulation of cellular metabolism, the size of cells, their proliferation and survival. RpS6 might stimulate or inhibit translation of certain mRNA. Upregulation of the gene is observed in pulmonary sclerosing hemangioma, lymphangioleiomyomatosis-associated angiomyolipomas, dysplasia, oral cavity and esophageal squamous cell carcinoma.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer.
Chen B
Journal of Experimental & Clinical Cancer Research, 34:126, 1-16 (2015)
Janice Chithelen et al.
Frontiers in physiology, 13, 856143-856143 (2022-04-05)
The bioactive sphingolipids ceramide and sphingosine-1-phosphate (S1P) are involved in the regulation of cell homeostasis and activity ranging from apoptosis to proliferation. We recently described that the two compounds ceranib-2 (inhibiting acid ceramidase) and SKI-II [inhibiting the sphingosine kinases 1
Aggregation of Ribosomal Protein S6 at Nucleolus Is Cell Cycle-Controlled and Its Function in Pre-rRNA Processing Is Phosphorylation Dependent.
Zhang D
Journal of Cellular Biochemistry, 117(7), 1649-1657 (2016)
Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway.
Presneau N
British Journal of Cancer, 100(9), 1406-1414 (2009)
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