产品名称
抗-视黄酸受体β,C-末端 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 50 kDa
species reactivity
mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RARB(5915)
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Biochem/physiol Actions
视黄酸受体β(RARB)可以与其配体视黄酸(RA))和类视黄醇相互作用,并在肺的正常发育中起着至关重要的作用。 它也参与哺乳动物上皮细胞的生长调节。 在各种癌症(包括甲状腺癌)中,RARB是一种肿瘤抑制蛋白。
该基因突变与无眼症和/或小眼症和膈疝的发生有关。由RARβ甲基化引起的RARβ基因失活可促进非小细胞肺癌(NSCLC)的发病机制,并成为NSLC的潜在生物标志物、风险因素和治疗靶标。
该基因突变与无眼症和/或小眼症和膈疝的发生有关。由RARβ甲基化引起的RARβ基因失活可促进非小细胞肺癌(NSCLC)的发病机制,并成为NSLC的潜在生物标志物、风险因素和治疗靶标。
Features and Benefits
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果,我们将给予您完全的赔偿或更换抗体。 了解更多。
General description
抗-维甲酸受体β抗体可检测总维甲酸受体β蛋白的内源性水平。
视黄酸受体β(RARB)由位于人类染色体3p24.2-p25上的基因所编码。编码的蛋白属于核受体超家族。
Immunogen
该抗血清是针对衍生自人维甲酸受体β的合成肽而制备的。
免疫原范围:331-380
免疫原范围:331-380
Physical form
兔IgG,溶于磷酸盐缓冲盐水(不含Mg2+和Ca2+),pH7.4,150mM NaCl,0.02%叠氮化钠和50%甘油中。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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K M Sommer et al.
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